The National Marrow Donor Program obtains hematopoietic stem cells from donors for recipients in need. When discussing this donation with the donor, what should the nurse know about these stem cells?
- A. They must come from an embryo or umbilical cord.
- B. These cells will form new blood cells for the recipient.
- C. Taking these cells will cause the donor to become anemic.
- D. These cells must be removed with a bone marrow aspiration.
Correct Answer: B
Rationale: Hematopoietic stem cells donated through programs like the National Marrow Donor Program help generate new blood cells for recipients, aiding in treating various blood disorders.
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NOD2
- A. Is a cytosolic receptor for bacteria
- B. Is mutated in 30% of patients with Crohn's disease
- C. Activates NFκB
- D. All of the above is correct
Correct Answer: D
Rationale: Step-by-step rationale:
1. NOD2 is a cytosolic receptor for bacteria, detecting bacterial molecules.
2. Mutations in NOD2 are found in 30% of patients with Crohn's disease.
3. NOD2 activation triggers NFκB signaling pathway.
4. Therefore, all the statements (A, B, C) are correct, making option D the correct answer. Other choices are incorrect as they do not encompass all the correct statements about NOD2.
What effect does the action of the complement system have on inflammation?
- A. Modifies the inflammatory response to prevent stimulation of pain
- B. Increases body temperature, resulting in destruction of microorganisms
- C. Produces prostaglandins and leukotrienes that increase blood flow, edema, and pain
- D. Increases inflammatory responses of vascular permeability, chemotaxis, and phagocytosis
Correct Answer: D
Rationale: The complement system enhances inflammation by increasing vascular permeability, attracting immune cells (chemotaxis), and promoting phagocytosis of pathogens or debris.
What are characteristics of the phosphate buffer system (select all that apply)?
- A. Neutralizes a strong base to a weak base and water
- B. Resultant sodium biphosphate is eliminated by kidneys
- C. Free acid radicals dissociate into H+ and CO2,buffering excess base
- D. Neutralizes a strong acid to yield sodium biphosphate,a weak acid and salt
Correct Answer: B
Rationale: Phosphate buffers neutralize strong bases/acid, form sodium biphosphate, and eliminate it through the kidneys.
Which of the following precautions must a nurse take while caring for clients with HIV/AIDS to reduce occupational risks?
- A. Transport specimens of body fluids in leak proof containers.
- B. Seek prescription for a fusion inhibitor to reduce risk of infection.
- C. Avoid administering IV drugs.
- D. Avoid cleaning the client’s room,especially cleaning urine,stoolor vomit.
Correct Answer: A
Rationale: Transporting specimens in leak-proof containers minimizes the risk of exposure to infectious body fluids.
Colostrum, the yellowish fluid, secreted by mother during the initial days of lactation is very essential to impart immunity to the newborn infants because it contains:
- A. Natural killer cells
- B. Monocytes
- C. Macrophages
- D. Immunoglobulin A
Correct Answer: D
Rationale: The correct answer is D: Immunoglobulin A. Colostrum contains high levels of Immunoglobulin A (IgA), which is crucial for imparting passive immunity to the newborn. IgA helps protect the infant's mucosal surfaces from infections. Natural killer cells, monocytes, and macrophages are not typically found in colostrum and are not responsible for conferring immunity to the newborn.