The normal microflora is related to the defense in pathogens in
- A. circulatory system
- B. hepatobiliary tract
- C. skin and mucus
- D. CNS
Correct Answer: C
Rationale: The normal microflora plays a crucial role in defending against pathogens in the skin and mucus. This is because the skin and mucus act as physical barriers and the normal microflora outcompetes potential pathogens, preventing their colonization. In contrast, the circulatory system (A), hepatobiliary tract (B), and CNS (D) are not typically colonized by normal microflora, so they do not directly contribute to defense against pathogens in those areas.
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The polymerase chain reaction CAN NOT be applied:
- A. To prove latent infection
- B. For rapid diagnosis of infectious diseases
- C. To determine the antibiotic susceptibility of microorganisms
- D. To demonstrate DNA and RNA molecule
Correct Answer: C
Rationale: The correct answer is C: To determine the antibiotic susceptibility of microorganisms. PCR is not suitable for determining antibiotic susceptibility as it is a technique used to amplify DNA/RNA, not to test for antibiotic resistance. To prove latent infection (A), PCR can be used to detect low levels of pathogens. For rapid diagnosis of infectious diseases (B), PCR is commonly used due to its sensitivity and specificity. To demonstrate DNA and RNA molecules (D), PCR is ideal as it can amplify and detect specific sequences. Therefore, choice C is incorrect as PCR is not designed for determining antibiotic susceptibility.
A laboratory received a sample of water used in drug production for sanitary and viral analysis. What group of viruses will indicate fecal contamination of water and thus the need for its additional purification?
- A. Picornaviridae
- B. Herpesviridae
- C. Flaviviridae
- D. Retroviridae
Correct Answer: A
Rationale: The correct answer is A: Picornaviridae. Picornaviruses, such as enteroviruses, are commonly found in the feces of infected individuals. Therefore, their presence in water indicates fecal contamination and the need for additional purification.
B: Herpesviridae are not typically associated with fecal contamination.
C: Flaviviridae are mainly transmitted through arthropods like mosquitoes, not fecal contamination.
D: Retroviridae, including HIV, are not typically excreted in high levels in feces and are not indicators of fecal contamination.
The term “infectious process†means “all biological processes carried out after…â€
- A. The attachment and penetration of microbes into the microorganism
- B. The attachment and penetration of microbes into the microorganisms regardless of whether or not there is clinical manifestation
- C. The penetration of microbes into the macroorganism and always manifest clinically
- D. No correct answer
Correct Answer: B
Rationale: The correct answer is B because the term "infectious process" refers to all biological processes that occur after the attachment and penetration of microbes into the host organism, regardless of whether there are clinical manifestations. This includes the colonization, multiplication, and spread of the microorganisms within the host.
Explanation:
A: Incorrect because it only mentions the attachment and penetration of microbes into the microorganism, missing the subsequent processes.
C: Incorrect because it is too specific, stating that the penetration of microbes always manifests clinically, which is not always the case.
D: Incorrect because there is a correct answer, which is B, as explained above.
A patient with pneumonia had sputum cultured, revealing Gram-negative diplococci. The bacteria were oxidase-positive and fermentative. What is the most likely causative agent?
- A. Neisseria meningitidis
- B. Neisseria gonorrhoeae
- C. Moraxella catarrhalis
- D. Haemophilus influenzae
Correct Answer: A
Rationale: The correct answer is A: Neisseria meningitidis. This is because Neisseria meningitidis is a Gram-negative diplococcus that is oxidase-positive and fermentative. Neisseria gonorrhoeae is also a Gram-negative diplococcus, but it is not fermentative. Moraxella catarrhalis is oxidase-positive but not fermentative. Haemophilus influenzae is Gram-negative but is not a diplococcus, and it is not fermentative. Therefore, based on the characteristics provided in the question, Neisseria meningitidis is the most likely causative agent.
Which of the following bacteria is responsible for causing bacterial meningitis?
- A. Neisseria meningitidis
- B. Haemophilus influenzae
- C. Streptococcus pneumoniae
- D. All of the above
Correct Answer: D
Rationale: The correct answer is D because all three bacteria (Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae) can cause bacterial meningitis. Neisseria meningitidis is a common cause of meningococcal meningitis, Haemophilus influenzae can cause H. influenzae meningitis, and Streptococcus pneumoniae is a leading cause of pneumococcal meningitis. Therefore, all of the above choices are correct. The other choices are incorrect because each of the bacteria listed can independently cause bacterial meningitis, so none of them alone can be the sole correct answer.