Nokea
The nucleocapsid of viruses consists of
- A. genome and envelop
- B. genome and capsid
- C. capsid and spikes
- D. capsid and envelop
Correct Answer: B
Rationale: The correct answer is B because the nucleocapsid of viruses is composed of the genome (genetic material) and the capsid (protein coat). The genome contains the viral genetic information, while the capsid protects the genome and helps in viral attachment and entry into host cells.
Choice A is incorrect because the envelope is not part of the nucleocapsid but surrounds the capsid in some viruses. Choice C is incorrect as spikes are surface proteins on the viral envelope, not part of the nucleocapsid. Choice D is also incorrect because the envelope is external to the capsid and genome in many viruses.
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Infections of Legionella pneumophila are treated with:
- A. Penicillins and cephalosporins
- B. Ethambutol and isoniazid
- C. Macrolides or fluoroquinolones
- D. Second and third generation cephalosporins
Correct Answer: C
Rationale: The correct answer is C: Macrolides or fluoroquinolones. Legionella pneumophila is a bacterium that causes Legionnaires' disease, a severe form of pneumonia. Macrolides (like azithromycin) and fluoroquinolones (like levofloxacin) are the recommended first-line treatments due to their ability to penetrate into lung tissues where Legionella infects. Penicillins and cephalosporins (choice A) are not effective against Legionella as it is intracellular and resistant to these antibiotics. Ethambutol and isoniazid (choice B) are used to treat tuberculosis, not Legionella infections. Second and third generation cephalosporins (choice D) are also not effective against Legionella. Therefore, the best choice for treating Legionella pneumophila infections is macrolides or fluoroquinolones.
A patient with pulmonary tuberculosis is prescribed the most effective antituberculosis antibiotic. Name this drug:
- A. Tetracycline
- B. Furasolidone
- C. Rifampicin
- D. Bactrim (Co-trimoxazole)
Correct Answer: C
Rationale: Rifampicin is the correct answer because it is a first-line antibiotic for treating pulmonary tuberculosis. It has excellent bactericidal activity and penetrates well into lung tissues where the infection is located. Rifampicin is also known for preventing the development of resistance. Tetracycline (A) and Furasolidone (B) are not commonly used for tuberculosis treatment. Bactrim (D) is a combination of sulfamethoxazole and trimethoprim, not effective for tuberculosis treatment.
Which of the following bacteria is responsible for causing bacterial meningitis?
- A. Neisseria meningitidis
- B. Haemophilus influenzae
- C. Streptococcus pneumoniae
- D. All of the above
Correct Answer: D
Rationale: The correct answer is D because all three bacteria (Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae) can cause bacterial meningitis. Neisseria meningitidis is a common cause of meningococcal meningitis, Haemophilus influenzae can cause H. influenzae meningitis, and Streptococcus pneumoniae is a leading cause of pneumococcal meningitis. Therefore, all of the above choices are correct. The other choices are incorrect because each of the bacteria listed can independently cause bacterial meningitis, so none of them alone can be the sole correct answer.
The colonies of the fungi that grow on solid media are called:
- A. Hyphae
- B. Mycelium
- C. Spore
- D. Columella
Correct Answer: B
Rationale: The correct answer is B: Mycelium. Mycelium refers to the network of branching filaments that form the main body of a fungus. When fungi grow on solid media, they develop a visible mass of mycelium. Hyphae (A) are the individual filaments that make up mycelium. Spores (C) are reproductive cells produced by fungi. Columella (D) refers to a specialized structure found in some fungi but is not related to the colonies grown on solid media. Therefore, the correct term for the colonies of fungi on solid media is mycelium.
Which of the following bacteria is responsible for causing the plague?
- A. Yersinia pestis
- B. Clostridium difficile
- C. Neisseria gonorrhoeae
- D. Pseudomonas aeruginosa
Correct Answer: A
Rationale: The correct answer is A: Yersinia pestis. Y. pestis is responsible for causing the plague, a severe infectious disease. This bacterium is transmitted via fleas from rodents to humans. It causes bubonic, septicemic, and pneumonic plague. Clostridium difficile causes gastrointestinal infections, Neisseria gonorrhoeae causes gonorrhea, and Pseudomonas aeruginosa can cause various infections but not the plague.