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The nurse admits a patient to the unit and learns the patient has recently been diagnosed with chronic renal failure but has not informed the primary care provider of this diagnosis. What is the nurse's first priority?
- A. Administer medications ordered immediately.
- B. Maintain the patient's confidentiality.
- C. Call the admitting physician immediately.
- D. Provide teaching about chronic renal failure
Correct Answer: C
Rationale: Renal failure affects drug clearance; informing the physician ensures safe therapy adjustments.
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Which of the following drugs interacts with nitroglycerine by inhibiting the metabolism of cGMP?
- A. Amyl nitrite
- B. Sildenafil
- C. Isosorbide mononitrate
- D. Nifedipine
Correct Answer: B
Rationale: Sildenafil, a PDE5 inhibitor, increases cGMP, enhancing nitroglycerin's hypotensive effect.
What factor influences drug absorption?
- A. Kidney function
- B. Route of administration
- C. Liver function
- D. Cardiovascular function
Correct Answer: B
Rationale: Drug absorption is influenced by the route of administration. IV administration is the fastest method; drug absorption is slower when given orally. Kidney function impacts excretion, liver function impacts metabolism, and cardiovascular function impacts distribution.
Which of the following is a disadvantage of IM administration?
- A. Larger volumes can be used
- B. Can affect lab tests
- C. Painful
- D. B and C
Correct Answer: C
Rationale: Intramuscular (IM) administration is painful due to needle insertion, though larger volumes are an advantage; affecting lab tests is less specific, making C the primary disadvantage.
What does the nurse understand must occur in order to produce withdrawal syndrome?
- A. Addiction
- B. Craving
- C. Drug tolerance
- D. Physical dependence
Correct Answer: D
Rationale: Physical dependence causes withdrawal when a drug stops; addiction or tolerance don't suffice. Patients who develop a physical dependence on a drug will experience withdrawal syndrome when the drug is stopped.
A client newly diagnosed with diabetes tells the nurse, 'I can't take any insulin made from pigs or cows.' Which of the following responses by the nurse is best?
- A. Most insulin comes from animal sources, but I'm sure alternative options are available.'
- B. Medications that are derived from animals are typically less expensive than synthetic medications, but synthetic insulin is commonly available.'
- C. Most insulin is synthetic now to help reduce the risk of disease transmission.'
- D. The animals aren't hurt in the production of medications, so you don't need to worry.'
Correct Answer: C
Rationale: Most insulin today is synthetic (e.g., recombinant DNA technology), reducing disease transmission risks and addressing patient concerns about animal sources effectively.