Nokea
Which of the following is the mechanism of action of iodides:
- A. Inhibits organification of iodine
- B. By inhibiting \mathrm{Na}+/ \mathrm{l} - simporter reduce iodine transport in thyroid gland
- C. Inhibits production of trioodthyronine form tetraiodthyronine on periphery
- D. Stimulates peroxidase
Correct Answer: A
Rationale: Iodides inhibit iodine organification, reducing thyroid hormone synthesis in high doses.
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While receiving treatment for acute pulmonary edema, a woman complains of tinnitus and vertigo.
- A. Clomiphene
- B. Hydrochlorothiazide
- C. Furosemide
- D. Mifepristone
Correct Answer: C
Rationale: Furosemide, a loop diuretic, can cause ototoxicity (tinnitus, vertigo) at high doses.
What is medication reconciliation?
- A. Comparing the patient's current medication orders to all of the medications actually being taken
- B. The administration of high alert medications that have been ordered on admission to an acute care facility
- C. The completion of an incident report following a variance that resulted in a serious complication
- D. A printout of computerized patient data that identifies the times that all of the ordered medications are to be administered
Correct Answer: A
Rationale: Medication reconciliation is the process of comparing a patient's current medication orders to all of the medications that the patient is actually taking. Administering high alert medications and completing an incident report are not the same as medication reconciliation. A printout of computerized patient data that identifies the times that all of the ordered medications are to be administered is a description of the medication administration record (MAR), not a description of medication reconciliation.
A nurse is reviewing laboratory findings and notes that a client's plasma Lithium level is 2.1 mEq/L. Which of the following is an appropriate action by the nurse?
- A. Perform immediate gastric lavage.
- B. Prepare the client for hemodialysis.
- C. Administrative and additional oral dose of lithium.
- D. Request a stat repeat of the laboratory test
Correct Answer: B
Rationale: A level of 2.1 mEq/L indicates toxicity (normal 0.6-1.2 mEq/L); hemodialysis is used for severe cases.
Which of the following is not hypoglicemic mechanism of action of metformin?
- A. Enhance insulin release by pancreatic beta cells
- B. Increase cell permeability of glucose and utilisation
- C. Decrease gluconeogenesis
- D. Interfere carbohydrate absorption in the gut
Correct Answer: A
Rationale: Metformin does not enhance insulin release; it improves insulin sensitivity and reduces hepatic glucose production.
A nurse is preparing to administer clindamycin 200 mg by intermittent IV bolus. The amount available is clindamycin injection 200 mg in 100 mL 0.9% sodium chloride (0.9% NaCl) to infuse over 30 min. The nurse should set the IV pump to deliver how many mL/hr? (Round the answer to the nearest whole number. Do not use a trailing zero.)
- A. 200
- B. 180
- C. 250
- D. 500
Correct Answer: A
Rationale: Calculation: (100 mL / 30 min) 60 min/hr = 200 mL/hr, matching the provided answer.