Free NCLEX RN Exam Related

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The nurse is caring for a client with a diagnosis of rheumatoid arthritis who is receiving methotrexate. Which laboratory value would be most concerning?

  • A. WBC 4,000/mm3
  • B. Platelet count 150,000/mm3
  • C. Hemoglobin 13 g/dL
  • D. Serum creatinine 1.2 mg/dL
Correct Answer: A

Rationale: Methotrexate can cause bone marrow suppression. A WBC of 4,000/mm3 (A) indicates leukopenia, increasing infection risk, and is most concerning. Platelets (B), hemoglobin (C), and creatinine (D) are within normal limits.