NCLEX Pharmacology Cheat Sheet Related

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The nurse is caring for a client with schizophrenia who has been treated with quetiapine (Seroquel) for 1 month. Today the client is increasingly agitated and complains of muscle stiffness. Which of these findings should be reported to the health care provider?

  • A. Elevated temperature and sweating
  • B. Decreased pulse and blood pressure
  • C. Mental confusion and general weakness
  • D. Muscle spasms and seizures
Correct Answer: A

Rationale: Elevated temperature and sweating. Neuroleptic malignant syndrome (NMS) is a rare disorder that can occur as a side effect of antipsychotic medications. It is characterized by muscular rigidity, tachycardia, hyperthermia, sweating, altered consciousness, autonomic dysfunction, and increase in CPK. This is a life-threatening complication.