Lewis's Medical Surgical Nursing in Canada, 5th Edition - Altered Immune Response and Transplantation Related

Review Lewis's Medical Surgical Nursing in Canada, 5th Edition - Altered Immune Response and Transplantation related questions and content

The nurse is caring for a patient who had a bone marrow transplant for treatment of leukemia and has developed a skin rash 10 days after the transplant. The nurse recognizes this reaction as an indication of which of the following?

  • A. Donor T cells are attacking the patient's skin cells.
  • B. The patient's antibodies are rejecting the donor bone marrow.
  • C. The patient is experiencing a delayed hypersensitivity reaction.
  • D. The patient will need treatment to prevent hyperacute rejection.
Correct Answer: A

Rationale: The patient's history and symptoms indicate that the patient is experiencing graft-versus-host disease, in which the donated T cells attack the patient's tissues. The history and symptoms are not consistent with rejection or delayed hypersensitivity.