The nurse is explaining how medications work to a group of peers and explains that disruption of a single step in any enzyme system disrupts what?
- A. Cell life
- B. Cell membrane
- C. Cell receptor sites
- D. Cell function
Correct Answer: D
Rationale: If a single step in one of the many enzyme systems is blocked, normal cell function is disrupted. Cell life and cell membrane may be impacted by disruption of some enzymes but not all enzymes. Receptor sites would not be disrupted by disruption in a single step in the enzyme system.
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Which of the following is a luminal amebecide drug?
- A. Metronidazole
- B. Emtine
- C. Doxycycline
- D. Dicloxinide
Correct Answer: D
Rationale: Diloxanide (likely misspelled as Dicloxinide) is a luminal amebicide used to eradicate cysts of Entamoeba histolytica in the intestinal lumen, unlike metronidazole, which targets systemic infection.
What is correct concerning TI:
- A. A safer drug has a higher theraputic index
- B. TI might be equal to 1
- C. The more the unwanted adverse effect, the ration decreases
- D. You are in danger if you take 1.8 ng/ml of Digoxin which has the margin of safety (0.8-2)
Correct Answer: A
Rationale: A higher therapeutic index indicates a greater margin of safety between therapeutic and toxic doses, making the drug safer.
A nurse has administered drugs to a patient as per the physician's orders. Which of the following activities should the nurse perform after administering the prescribed drugs to the patient?
- A. Record symptoms of the condition.
- B. Perform a culture and sensitivity test.
- C. Obtain history of drug allergy.
- D. Check for adverse drug reactions.
Correct Answer: D
Rationale: After administering the drug to the patient, the nurse should observe the patient for adverse drug reactions. Recording symptoms of infection, performing a culture and sensitivity test, and obtaining a history of drug allergy are typically performed by the nurse in the preadministration assessment stage.
T½ of a drug can determine all the following
- A. Closing interval
- B. Elimination time
- C. Steady Plasma Concentration
- D. Therapeutic dosage
Correct Answer: D
Rationale: Half-life (t½) informs dosing intervals to maintain therapeutic levels.
A nurse is preparing to administer Filgrastim for the first time to a client who has just undergone a bone marrow transplant. Which of the following interventions is appropriate?
- A. Administer IM in a large muscle mass to prevent injury.
- B. Ensure that the treatment of the patient is a non-... (truncated)
Correct Answer: C
Rationale: Filgrastim is typically given subcutaneously or IV, not IM; the truncated option suggests a typo, but standard practice is assumed.