The nurse is explaining the Human Genome Project to colleagues. Which of these is the main purpose of the Human Genome Project?
- A. The study of genetic diseases
- B. The study of genetic traits in humans
- C. The discovery new genetic diseases
- D. To describe the entire genome of a human being
Correct Answer: D
Rationale: The Human Genome Project was undertaken to describe in detail the entire genome of a human being. The other options do not describe the Human Genome Project.
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The nurse is preparing a class on gene therapy for a group of students. Which statements about gene therapy are true?
- A. The FDA must review and approve all human clinical genetic trials.
- B. Gene therapy may involve creating new genes within a human.
- C. Gene therapy may involve replacing a mutated gene with a healthy copy of the gene.
- D. Some trials involve introducing a new gene into the body to help fight disease.
- E. Gene therapy may include inactivating a mutated gene that is not functioning properly.
Correct Answer: A,C,D,E
Rationale: Gene therapy may include: Replacing a mutated gene with a healthy copy of the gene; introducing a new gene into the body to help fight a disease; inactivating a mutated gene that is functioning improperly. In addition, the FDA must review and approve all human clinical genetic trials. Gene therapy does not include creating new genes.
A patient will be receiving famotidine 20 mg at bedtime. A liquid form is ordered because the patient cannot swallow pills or capsules; the concentration of the liquid is 40 mg/5 mL. How many milliliters will the patient receive per dose?
Correct Answer: 2.5 mL
Rationale: 40 mg : 5 mL :: 20 mg : x mL; (40 * x) = (5 * 20); 40x = 100; x = 2.5 mL/dose.
The nurse is asking a patient about his family history as part of an assessment. Which component is included in an effective family history?
- A. Asking the patient about the current and past health status of the patient's children
- B. Covering at least three generations of family history
- C. Obtaining a family history of the patient's spouse
- D. Asking about the family history for the patient's siblings and parents only
Correct Answer: B
Rationale: The family history is most effective if it covers at least three generations and includes the current and past health status of each family member. The other options are incorrect.
The nurse is discussing gene therapy in a continuing education class. Which is the best definition of eugenics?
- A. The use of gene therapy to prevent disease
- B. The development of new drugs based on gene therapy
- C. Intentional selection, before birth, of genotypes that are considered more desirable than others
- D. The determination of genetic factors that influence a person's response to medications
Correct Answer: C
Rationale: Eugenics is the intentional selection of genotypes, before birth, that are considered more desirable than others, and it is a major ethical issue concerning gene therapy. The other options do not describe eugenics.
The nurse is reviewing the applications of gene therapy. Which drug is manufactured as a result of indirect gene therapy?
- A. Vitamin K
- B. Warfarin
- C. Human insulin
- D. Heparin
Correct Answer: C
Rationale: A recombinant form of human insulin is one of the most widespread uses of indirect gene therapy. Other examples include hormones, vaccines, antitoxins, and monoclonal antibodies. The other options listed are not examples of drugs manufactured by indirect gene therapy.
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