Roach's Introductory Clinical Pharmacology 11th Edition - Antipsychotic Drugs Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Antipsychotic Drugs related questions and content

The nurse is providing care to a client receiving clozapine (Clozaril). The nurse would be alert for an increased risk of bone marrow suppression if the client is also receiving which of the following? Select all that apply.

  • A. Immunological agents
  • B. Anticholinergics
  • C. Opioids
  • D. Anticoagulants
Correct Answer: A

Rationale: The concomitant use of clozapine and immunological drugs can increase the severity of bone marrow suppression. The use of anticholinergics in combination with antipsychotics can increase the risk of tardive dyskinesia and psychotic symptoms. Opioids and anticoagulants are not associated with interactions involving antipsychotic drugs.