The nurse is reviewing new postoperative orders and notes that the order reads, 'Give hydroxyzine 50 mg IV PRN nausea or vomiting.' The patient states that he has slight nausea. Which action by the nurse is correct at this time?
- A. Hold the dose until the patient states that the nausea is severe.
- B. Give the dose orally instead of intravenously.
- C. Give the patient the IV dose of hydroxyzine as ordered.
- D. Call the prescriber to question the route that is ordered.
Correct Answer: D
Rationale: The nurse needs to question the route. Hydroxyzine is an antihistamine-class antiemetic that is only to be given either by oral or intramuscular routes. Intravenous, intra-arterial, or subcutaneous administration of hydroxyzine may result in significant tissue damage, thrombosis, and gangrene. Antiemetic drugs are best given before the patient's nausea becomes severe.
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A patient on chemotherapy is using ondansetron for treatment of nausea. The nurse will instruct the patient to watch for which adverse effect of this drug?
- A. Dizziness
- B. Diarrhea
- C. Dry mouth
- D. Blurred vision
Correct Answer: B
Rationale: Diarrhea is an adverse effect of the serotonin blockers. The other adverse effects listed may occur with anticholinergic drugs.
An adult patient is about to receive intravenous (IV) ondansetron during a chemotherapy treatment. A dose of 0.15 mg/kg IV 30 minutes before chemotherapy is ordered. The patient weighs 165 pounds. The medication is supplied in a vial marked 2 mg/mL for IV administration. Identify how many milliliters the nurse will administer for this dose. (Record answer to one decimal place.)
Correct Answer: 5.7 mL
Rationale: Convert pounds to kilograms: 165 ?· 2.2 = 75 kg. Calculate milligrams per dose: 0.15 mg/kg ?? 75 kg = 11.25 mg, rounded to 11.3 mg/dose. Calculate milliliters to be given: 2 mg:1 mL::11.3 mg:x mL, (2 ?? x) = (1 ?? 11.3); 2x = 11.3, x = 5.65, which rounds to 5.7 mL.
A patient is taking chemotherapy with a drug that has a high potential for causing nausea and vomiting. The nurse is preparing to administer an antiemetic drug. Which class of antiemetic drugs is most commonly used to prevent nausea and vomiting for patients receiving chemotherapy?
- A. Prokinetic drugs, such as metoclopramide
- B. Serotonin blockers, such as ondansetron
- C. Anticholinergic drugs, such as scopolamine
- D. Neuroleptic drugs, such as promethazine
Correct Answer: B
Rationale: Serotonin blockers are used to prevent chemotherapy-induced and postoperative nausea and vomiting.
A patient with motion sickness is planning a cross-country car trip and has a new prescription for a scopolamine transdermal patch. The nurse provides teaching for the use of this patch medication. The patient shows a correct understanding of the teaching with which statement?
- A. I will change the patch every day.
- B. I will change the patch every other day.
- C. I will change the patch every 3 days.
- D. I will remove the patch only if it stops working.
Correct Answer: C
Rationale: Scopolamine patches are 72-hour doses and therefore are changed every 3 days.
A patient is receiving a tube feeding through a gastrostomy. The nurse expects that which type of drug will be used to promote gastric emptying for this patient?
- A. Prokinetic drugs, such as metoclopramide
- B. Serotonin blockers, such as ondansetron
- C. Anticholinergic drugs, such as scopolamine
- D. Neuroleptic drugs, such as chlorpromazine
Correct Answer: A
Rationale: Prokinetic drugs promote the movement of substances through the gastrointestinal tract and increase gastrointestinal motility.
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