Pediatric Emergency Nursing PICO Questions Related

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The screening test for PKU is most reliable if the blood sample is:

  • A. from cord blood.
  • B. taken 14 days after birth.
  • C. taken before oral feedings are initiated.
  • D. fresh blood from the heel.
Correct Answer: D

Rationale: The screening test for PKU (Phenylketonuria) is most reliable when the blood sample is fresh and taken from the heel. This is because the test requires a small amount of blood, and obtaining a fresh sample from the heel minimizes the risk of contamination and ensures accurate results. Additionally, collecting the blood sample from the heel is less invasive for the newborn and is a common practice for newborn screening tests. Blood samples taken from cord blood, 14 days after birth, or before oral feedings are initiated may not provide accurate results for the PKU screening test.