Nokea
The study of dose, distribution, metabolism & excretion of drugs in the body is known as
- A. Pharmacognosia
- B. Pharmacodynamics
- C. Dose effective study
- D. Pharmacotherapy
Correct Answer: B
Rationale: Pharmacodynamics studies drug effects, but pharmacokinetics (dose, distribution, metabolism, excretion) is more specific here; likely a typo in the document.
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Flushing occurs when alcohol is taken along with
- A. Phenformin
- B. Chlorpropamide
- C. Glibenclamide
- D. Tolbutamide
Correct Answer: B
Rationale: Chlorpropamide causes a disulfiram-like reaction with alcohol, leading to flushing.
Laboratory monitoring for patients on angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers should include:
- A. White blood cell counts with the drug dosage increased for elevations above 10,000 feet
- B. Liver function tests with the drug dosage stopped for alanine aminotransferase values twice that of normal
- C. Serum creatinine levels with the drug dosage reduced for values greater than 2.5 mg/dL
- D. Serum glucose levels with the drug dosage increased for levels greater than 120 mg/dL
Correct Answer: C
Rationale: Elevated creatinine (>2.5 mg/dL) indicates renal impairment, requiring dose adjustment.
The bronchodilator of choice for patients taking propranolol is:
- A. Albuterol
- B. Pirbuterol
- C. Formoterol
- D. Ipratropium
Correct Answer: D
Rationale: Ipratropium , an anticholinergic, avoids beta-blockade interference from propranolol, unlike beta-agonists .
Which of the following antiarrhythmic agents has the longest plasma half-life?
- A. Amiodarone
- B. Disopyramide
- C. Quinidine
- D. Disopyramide
Correct Answer: A
Rationale: Amiodarone has a half-life of weeks due to extensive tissue distribution.
When the costs of a specific treatment or intervention are calculated and then compared with the dollar value of the benefit received it is referred to as:
- A. Cost-minimization analysis
- B. Cost-of-illness analysis
- C. Cost-effectiveness analysis
- D. Cost-benefit analysis
Correct Answer: D
Rationale: Cost-benefit analysis quantifies both costs and benefits in monetary terms.