The test used to differentiate sickle cell trait from sickle cell disease is:
- A. sickle cell preparation
- B. peripheral smear
- C. sickledex
- D. hemoglobin electrophoresis
Correct Answer: D
Rationale: Hemoglobin electrophoresis identifies the specific hemoglobin types, distinguishing sickle cell trait (HbAS) from sickle cell disease (HbSS).
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Prior to administering filgrastim, the nurse reviews the laboratory report results for the 3-year-old who completed the second round of chemotherapy three weeks ago. Which finding indicates a therapeutic response to filgrastim?
- A. Hematocrit of 31%
- B. Eosinophil count of 6%
- C. WBC count of 6800/mm3
- D. Platelet count of 150,000/mm3
Correct Answer: C
Rationale: A: The Hct of 31% is normal but is unaffected by filgrastim, a colony-stimulating factor. B: The eosinophil count of 6% is elevated (0 to 2% is normal) but is not related to filgrastim use. C: Filgrastim (Neupogen) is a colony-stimulating factor used to increase the production of WBCs in persons who have bone marrow depression from chemotherapy. D: The platelet count of 150,000/mm3 is normal but is not used to evaluate the therapeutic effectiveness of filgrastim.
The clinic nurse is reviewing prescriptions with the parents of the school-aged child with newly diagnosed generalized contact dermatitis. Which prescription should the nurse question with the HCP?
- A. Oral prednisone
- B. Calamine lotion
- C. Oral diphenhydramine
- D. Hydrocortisone cream
Correct Answer: A
Rationale: A: Prednisone (Deltasone) would not be a first-line treatment for contact dermatitis, and its use should be questioned. Prednisone may be added later if the contact dermatitis has not resolved. B: Calamine lotion is used to promote drying and help relieve itching. C: Diphenhydramine (Benadryl) helps to relieve itching. D: Hydrocortisone cream is an anti-inflammatory agent used to treat contact dermatitis.
A client who is newly diagnosed with Parkinson's disease and beginning medication therapy asks the nurse, 'How soon will I see improvement?' The nurse's best response is:
- A. That varies from client to client
- B. You should discuss that with your physician
- C. You should notice a difference in a few days
- D. It might take several weeks before you notice improvement
Correct Answer: D
Rationale: Parkinson's medications often take several weeks to show improvement, as they gradually adjust neurotransmitter levels to manage symptoms.
Around what age do children start to develop "stranger anxiety"?
- A. 9 months
- B. 6 months
- C. 3 months
- D. 12 months
Correct Answer: B
Rationale: By 6 months, children should be able to recognize familiar faces, and thus they are aware of strangers. Strangers may illicit anxiety.
The HCP orders a digitalizing dose of digoxin 225 mcg IV now to be given to a 3-year-old. The pharmacy sends a solution of 500 mcg in 50 mL of D5W. How many mL should the nurse administer?
Correct Answer: 22.5
Rationale: Use a proportion formula: 500 mcg : 50 mL :: 225 mcg : X mL; 500X = 11250; X = 22.5 mL.
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