Nokea
The thickening of the glomerular basal membrane in an early stage of diabetes mellitus is a consequence of which mechanism?
- A. AGE deposition
- B. Proteinuria
- C. Inflammation
- D. All mechanisms mentioned above
Correct Answer: A
Rationale: Early diabetic kidney AGEs glue GBM thick, not protein spill or inflammation yet. Nurses catch this, a chronic sugar scar.
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In order to delay the progression of CKD, the single most important intervention is:
- A. Prescription of an ACE or ARB
- B. Reducing dietary sodium
- C. Increasing physical activity
- D. Achieving good blood pressure control
Correct Answer: D
Rationale: CKD's brake BP control tops ACEs, salt cuts, or workouts, slashing glomeruli strain, a chronic slowdown king. Nurses prioritize this, a pressure-driven win.
An oncology nurse educator is providing health education to a patient who has been diagnosed with skin cancer. The patient's wife has asked about the differences between normal cells and cancer cells. What characteristic of a cancer cell should the educator cite?
- A. Malignant cells contain more fibronectin than normal body cells
- B. Malignant cells contain proteins called tumor-specific antigens
- C. Chromosomes contained in cancer cells are more durable and stable than those of normal cells
- D. The nuclei of cancer cells are unusually large, but regularly shaped
Correct Answer: B
Rationale: Cancer cells sport tumor-specific antigens (e.g., CEA) proteins marking them as rogue, unlike normal cells. Fibronectin's less in malignant cells, aiding their slipperiness. Chromosomes are fragile and jumbled (aneuploidy), not stable. Nuclei are big and wonky (pleomorphic), not regular. Nurses in oncology education lean on this antigen trait it's why tests spot cancer and therapies target it, a clear line from normal to malignant.
A client with cancer is admitted to a short-term rehabilitation facility. The nurse prepares to administer the client's oral chemotherapy medications. What action by the nurse is most appropriate?
- A. Crush the medications if the client cannot swallow them.
- B. Give one medication at a time with a full glass of water.
- C. No special precautions are needed for these medications.
- D. Wear personal protective equipment when handling the medications.
Correct Answer: D
Rationale: Oral chemotherapy drugs, like their IV counterparts, are hazardous due to their cytotoxic properties, posing risks to healthcare workers through skin contact or inhalation during handling. The most appropriate action is for the nurse to wear personal protective equipment (PPE), such as gloves, to minimize exposure, aligning with oncology safety standards. Crushing these medications is contraindicated, as it increases the risk of aerosolizing toxic particles, endangering both nurse and client many are labeled do not crush.' Giving one at a time with water isn't necessary unless specified and doesn't address safety. Assuming no precautions are needed ignores the drugs' hazardous nature, risking occupational exposure. Using PPE ensures safe administration, protects the nurse's health, and maintains the medication's integrity, reflecting best practices in cancer care where handling precautions are non-negotiable.
A 65-year-old male client is brought via EMS to the emergency department with chest pain. He rates the pain as a 10 on a scale from 0-10; the pain is located mid-sternum and radiates to his left arm. His heart rate is 126 beats/minute and blood pressure are 96/60 mm Hg. A 12-lead electrocardiogram is performed and reveals ST-segment elevation. Which of the following interventions does the nurse anticipate performing immediately?
- A. Administer oxygen
- B. Administer morphine
- C. Administer a statin
- D. Administer nitroglycerin
Correct Answer: A
Rationale: ST-elevation MI (STEMI) signals acute coronary occlusion severe chest pain, tachycardia, and hypotension demand oxygen first to counter hypoxia, per ABCs, buying time for reperfusion. Morphine eases pain, nitroglycerin dilates (if BP allows), but oxygen's immediate. Statins aid long-term, not now. Nurses prioritize oxygen, anticipating cath lab prep, a critical step in this time-sensitive infarct emergency.
On a population level, differences can be observed between the body composition of people with and people without a disturbed glucose tolerance. Question: Which of the following options describes the body composition of overweight people with a disturbed glucose tolerance compared to that of healthy people without overweight?
- A. More adipose tissue and similar muscle mass
- B. More adipose tissue and less muscle mass
- C. More adipose tissue and more muscle mass
- D. More adipose tissue and less muscle mass, including a change in the ratio of different types of muscle fibres
Correct Answer: B
Rationale: Glucose tolerance tanks overweight pile fat, lose muscle, not same or more, no fibre shift specifics. Nurses see this, a chronic lean loss.