The U.S. Food and Drug Administration approval is required for:
- A. Medical devices, including artificial joints
- B. Over-the-counter vitamins
- C. Herbal products, such as St John's wort
- D. Dietary supplements, such as Ensure
Correct Answer: A
Rationale: FDA approval is required for medical devices like artificial joints , but not OTC vitamins, herbal products, or supplements (B-D), which have lighter oversight.
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Which of the following produced by the pancreatic beta cells:
- A. Insulin
- B. Gastrin
- C. Somatostatin
- D. Glucagon
Correct Answer: A
Rationale: Insulin is secreted by pancreatic beta cells to lower blood glucose.
Azathioprine is useful in the following diseases EXCEPT:
- A. Rheumatoid arthritis
- B. Psoriatic arthritis
- C. Reactive arthritis
- D. osteoarthritis
Correct Answer: D
Rationale: Azathioprine is not typically used for osteoarthritis, a degenerative condition.
What happens in the case of thyroid hormones triiodethyronine (T3) and tetraiodethyronine (T4) I the blood:
- A. Decrease thyrotropin hormone release in the blood
- B. Increase thyrotropin hormone release in the blood
- C. Decrease thyroid releasing hormone release in the blood
- D. Doesn't change thyrotropine and thyroid releasing hormone release
Correct Answer: A
Rationale: High T3 and T4 levels decrease TSH release via negative feedback on the pituitary.
Which of the following beta-blockers has intrinsic sympathomimetic activity (ISA)?
- A. Bisoprolol
- B. Timolol
- C. Pindolol
- D. Propanolol
Correct Answer: C
Rationale: Pindolol has ISA, partially stimulating beta receptors while blocking them, reducing bradycardia risk.
Donald has been diagnosed with hyperlipidemia. Based on his lipid profile, atorvastatin is prescribed. Rhabdomyolysis is a rare but serious adverse response to this drug. Donald should be told to:
- A. Become a vegetarian because this disorder is associated with eating red meat.
- B. Stop taking the drug if abdominal cramps and diarrhea develop.
- C. Report muscle weakness or tenderness and dark urine to his provider immediately.
- D. Expect 'hot flash' sensations during the first 2 weeks of therapy.
Correct Answer: C
Rationale: Muscle symptoms and dark urine indicate rhabdomyolysis, requiring immediate reporting.
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