Nokea
Third generation cephalosporin that is primarily excreted through bile is
- A. Cefoperazone
- B. Ceftriaxone
- C. Cefotaxim
- D. Cefixime
Correct Answer: A
Rationale: Cefoperazone is known for its biliary excretion
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The following are major side effects of PGE1 EXCEPT
- A. apnea
- B. fever
- C. cutaneous flushing
- D. hypertension
Correct Answer: D
Rationale: Cutaneous flushing is a common side effect of PGE1, while hypertension is not typically observed.
Azathioprine:
- A. Is a prodrug
- B. Is teratogenic
- C. Should be avoided in liver disease
- D. Dose should be increased when given with allopurinol
Correct Answer: A
Rationale: Azathioprine is a prodrug. It is not highly teratogenic, can be used in liver disease with caution, and its dose should be reduced with allopurinol.
In homo cystinuria:
- A. Homocysteine accumulates just proximal to the enzyme defect
- B. Osteoporosis is a recognised feature
- C. Oral contraceptive pills with oestrogens are contraindicated
- D. Dislocation of lens is a feature
Correct Answer: D
Rationale: Dislocation of the lens is a well-documented feature of homocystinuria due to the accumulation of homocysteine, which affects connective tissue.
Drug of choice for infective endocarditis due to HACEK organisms is
- A. Vancomycin
- B. Gentamicin
- C. Ampicillin
- D. Ceftriaxone
Correct Answer: D
Rationale: Ceftriaxone is the drug of choice for infective endocarditis due to HACEK organisms.
A 12-month-old infant who had cardiopulmonary bypass with RBC and plasma infusions during surgery at 8 months is seen for a well child examination. Which vaccine may be administered at this visit?
- A. Measles
- B. mumps
- C. and rubella (MMR)
- D. Oral polio vaccine (OPV)
Correct Answer: C
Rationale: Live vaccines should be delayed until 6 months after cardiopulmonary bypass and exposure to RBCs and plasma. PCV-13 is not a live-virus vaccine.