Nokea
This graph shows the concentration-dependent effects of norepinephrine on arterial blood pressure, both alone, and in the presence of a fixed concentration of Drug X. Which type of antagonist is Drug X?
- A. Silent
- B. Non-competitive
- C. Competitive
- D. Chemical
Correct Answer: B
Rationale: A non-competitive antagonist reduces the maximal response without shifting the potency (EC50), as indicated by the answer key, likely showing a decreased maximum on the graph.
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A nurse is instructing a client who has a new prescription for Timolol how to insert eye drops. The nurse should instruct the client to press on which of the following areas to prevent systemic absorption of the medication?
- A. Bony orbit
- B. Nasolacrimal duct
- C. Conjunctival sac
- D. Outer canthus
Correct Answer: B
Rationale: Pressing the nasolacrimal duct prevents systemic absorption by blocking drainage into the nasal cavity.
Which statement is correct regarding glucagon:
- A. Causes hypoglicemia
- B. Haven't affect glucose level in the blood
- C. Has a positive inotroic effect
Correct Answer: C
Rationale: Glucagon has a positive inotropic effect on the heart, increasing contractility, in addition to raising blood glucose levels.
A nurse is reviewing the health record of a client who asks about using Propranolol to treat hypertension. The nurse should recognize which of the following conditions is a contraindication for taking propranolol?
- A. Asthma
- B. Glaucoma
- C. Hypertension
- D. Tachycardia
Correct Answer: A
Rationale: Propranolol is contraindicated in asthma due to risk of bronchoconstriction.
When prescribing Adderall (amphetamine and dextroamphetamine) to adults with ADHD the nurse practitioner will need to monitor:
- A. Blood pressure
- B. Blood glucose levels
- C. Urine ketone levels
- D. Liver function
Correct Answer: A
Rationale: Adderall increases blood pressure, requiring monitoring.
A nurse is caring for a client who has Atrial Fibrillation and a new prescription for Dabigatran to prevent development of Thrombosis. Which of the following medications is prescribed concurrently to treat an adverse effect of Dabigatran?
- A. Vitamin k1
- B. Protamine
- C. Omeprazole
- D. Probenecid
Correct Answer: C
Rationale: Omeprazole reduces dabigatran's GI bleeding risk, a common side effect.