Nokea
Ultra-rapid metabolizers of drugs may have:
- A. To have dosages of drugs adjusted downward to prevent drug accumulation
- B. Active drug rapidly metabolized into inactive metabolites, leading to potential therapeutic failure
- C. Increased elimination of active, nonmetabolized drug
- D. Slowed metabolism of a prodrug into an active drug, leading to an accumulation of prodrug
Correct Answer: B
Rationale: Ultra-rapid metabolizers (e.g., CYP2D6) quickly inactivate drugs , risking therapeutic failure, requiring higher doses, not lower or slowed metabolism .
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A primary health care provider instructs a nurse to administer a medication to a patient STAT. Which action by the nurse would be most appropriate?
- A. Insist on obtaining a written report before administering any drug.
- B. Administer the drug as ordered by the physician.
- C. Forgo obtaining the physician's order after the drug has been administered.
- D. Document the administration of the drug only after receiving the physician's order.
Correct Answer: B
Rationale: The nurse should administer the drug as instructed without a written order as it is an emergency. The nurse should, however, ensure that the physician's order is obtained after the drug has been administered. Waiting for a written order during an emergency may exacerbate the patient's condition. The nurse should complete the documentation immediately after the administration of the drug and not wait until the physician's order is received.
Which is the most authoritative reference for medications that are injected?
- A. Martindale: The Complete
- B. Handbook on Injectable Drugs
- C. DailyMed
- D. Handbook of Nonprescription Drugs
Correct Answer: B
Rationale: The Handbook on Injectable Drugs is the most comprehensive reference available on the topic of compatibility of injectable drugs.
Janie presents to the clinic with hard ear wax in both ear canals. Instructions regarding home removal of hard cerumen include:
- A. Moisten a cotton swab (Q-tip) and swab the ear canal twice daily
- B. Instill tap water in both ears while bathing
- C. Squirt hydrogen peroxide into ears with each bath
- D. Instill carbamide peroxide (Debrox) twice daily until canals are clear
Correct Answer: D
Rationale: Carbamide peroxide softens cerumen safely; Q-tips risk impaction, and water or peroxide are less effective.
Strategies prescribers can use to prevent misuse of controlled prescription drugs include:
- A. Use of chemical dependency screening tools
- B. Firm limit-setting regarding prescribing controlled substances
- C. Practicing 'just say no' to deal with patients who are pushing the provider to prescribe controlled substances
- D. All of the above
Correct Answer: D
Rationale: All strategies "screening , limits , and refusal "help prevent misuse of controlled substances.
A nurse is teaching a client who has a new prescription for Brimonidine ophthalmic drops and wears soft contact lenses. Which of the following instructions should the nurse include in the teaching?
- A. This medication can stain your contacts.
- B. This medication can cause your pupils to constrict.
- C. This medication can absorb into your contacts.
- D. This medication can slow your heart rate.
Correct Answer: C
Rationale: Brimonidine can absorb into contacts , requiring removal before use to avoid irritation.