Viruses can infect
- A. plants.
- B. bacteria.
- C. animals.
- D. all organisms.
Correct Answer: D
Rationale: The correct answer is D because viruses have the ability to infect all organisms, including plants, bacteria, animals, and even fungi. Viruses are non-living entities that require a host cell to replicate and spread. They can infect a wide range of organisms by attaching to specific receptors on the host cell's surface. Therefore, the correct answer is D as viruses have the capability to infect all living organisms. Choices A, B, and C are incorrect because viruses can infect not only plants, bacteria, and animals but also other organisms, making choice D the most comprehensive and accurate option.
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Which is NOT a property of interferon?
- A. Released from infected cells
- B. Acts extracellularly to inactivate virus
- C. Coded for by cellular DNA
- D. Not virus-specific but is cell-specific
Correct Answer: D
Rationale: Interferon is a cell-specific protein that is produced and released from infected cells in response to viral infections. It acts extracellularly to interfere with viral replication, not to inactivate the virus itself. Interferon is not coded for by cellular DNA, but by viral RNA during infection. Therefore, the correct answer, D, is that interferon is not virus-specific but is cell-specific. This is because interferon can be produced by various cell types in response to different types of viral infections, making it a broad-spectrum antiviral defense mechanism.
Which of the following bacteria is capable of surviving in extreme heat?
- A. Escherichia coli
- B. Bacillus subtilis
- C. Staphylococcus aureus
- D. Clostridium botulinum
Correct Answer: B
Rationale: The correct answer is B: Bacillus subtilis. Bacillus subtilis is a thermophilic bacterium capable of surviving in extreme heat due to its heat-resistant spores. It forms spores when exposed to unfavorable conditions, allowing it to withstand high temperatures. Escherichia coli (A), Staphylococcus aureus (C), and Clostridium botulinum (D) are mesophilic bacteria that do not have the same heat resistance mechanisms as Bacillus subtilis, making them unable to survive in extreme heat conditions.
Which of the following organisms belongs in the group I category?
- A. Francisella tularensis
- B. Clostridium difficile
- C. Helicobacter pylori
- D. Bacillus anthracis
Correct Answer: C
Rationale: The correct answer is C: Helicobacter pylori. Group I organisms are classified based on their low infectious doses and potential for bioterrorism. H. pylori is known to cause gastric ulcers and is categorized as a Group I organism due to its ability to cause disease at low doses.
A: Francisella tularensis is a Group A bioterrorism agent, not Group I.
B: Clostridium difficile is not typically classified as a Group I organism.
D: Bacillus anthracis is a Group A bioterrorism agent, not Group I.
A patient with a wound infection had a Gram-positive cocci isolated from the sample. The bacteria were catalase-positive and coagulase-positive. What is the most likely causative agent?
- A. Staphylococcus aureus
- B. Staphylococcus epidermidis
- C. Streptococcus pyogenes
- D. Enterococcus faecalis
Correct Answer: A
Rationale: The correct answer is A: Staphylococcus aureus. Staphylococcus aureus is a Gram-positive cocci that is catalase-positive and coagulase-positive, making it the most likely causative agent for the wound infection. Catalase-positive bacteria produce the enzyme catalase, which helps break down hydrogen peroxide. Coagulase-positive bacteria produce the enzyme coagulase, which causes the plasma proteins to clot. Staphylococcus epidermidis is catalase-positive but coagulase-negative, making it less likely to cause a wound infection. Streptococcus pyogenes is catalase-negative, and Enterococcus faecalis is catalase-negative and coagulase-negative, so they are less likely to be the causative agent.
A 36-year-old man provisionally diagnosed with renal tuberculosis has undergone urinary sediment analysis. Microscopy revealed acid-fast bacteria, but Pryce method detected no cord factor. Name the most reliable method of investigation that can confirm or refute this provisional diagnosis:
- A. Inoculation of laboratory animals
- B. Phage typing of the obtained culture
- C. Allergy skin test
- D. Toxigenicity testing
Correct Answer: B
Rationale: The correct answer is B: Phage typing of the obtained culture. This method is used for typing Mycobacterium tuberculosis strains based on susceptibility to specific bacteriophages. If the culture shows susceptibility, it confirms the presence of M. tuberculosis. In this case, the absence of cord factor indicates that the bacteria are unlikely to be M. tuberculosis.
Option A (Inoculation of laboratory animals) is unethical and not necessary when other methods are available. Option C (Allergy skin test) is not relevant for confirming a diagnosis of renal tuberculosis. Option D (Toxigenicity testing) is not specific for confirming or refuting a diagnosis of M. tuberculosis.