Nokea
What condition is associated with C1q deficiency?
- A. Cancer
- B. Systemic lupus erythematosus (SLE)
- C. HIV/AIDS
- D. Chronic obstructive pulmonary disease
Correct Answer: B
Rationale: Rationale: C1q is a component of the classical complement pathway, crucial for immune complex clearance. Its deficiency is associated with SLE due to impaired immune complex removal, leading to autoantibody deposition and inflammation. Cancer, HIV/AIDS, and COPD are not directly linked to C1q deficiency.
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The nurse realizes that the patient understands the teaching about decreasing the risk for antibiotic-resistant infection when the patient says which of the following?
- A. I know I should take the antibiotic for one day after I feel better.
- B. I want an antibiotic ordered for my cold so I can feel better sooner.
- C. I always save some pills because I get the illness again after I first feel better.
- D. I will follow the directions for taking the antibiotic so I will get over this infection.
Correct Answer: D
Rationale: Following the prescribed regimen ensures complete eradication of the infection and reduces the risk of resistance development.
Which of the following statements is NOT true?
- A. Plague or Black Death is the disease that devastated Europe in Medieval times (1350-1400) with about 50% of the European population having been wiped out.
- B. There are reports of Black Death dating as early as 1000 B.C. making plague probably the most ancient disease and the first recorded
- C. Plague is still endemic in some countries
- D. Plague can be cured with antibiotics
Correct Answer: B
Rationale: The correct answer is B because there are no reports of the Black Death dating back to 1000 B.C. The Black Death specifically refers to the pandemic outbreak of the bubonic plague in the 14th century. The first recorded pandemic of the Black Death occurred in the 14th century, not in 1000 B.C. The other choices are incorrect because A is true as the Black Death did devastate Europe in the 14th century, C is true as plague is still present in some countries, and D is true as plague can be treated with antibiotics if caught early.
Which hypersensitivity type is mediated by T cells?
- A. Type I
- B. Type II
- C. Type III
- D. Type IV
Correct Answer: D
Rationale: The correct answer is D: Type IV hypersensitivity. This type is mediated by T cells, specifically CD4+ helper T cells and CD8+ cytotoxic T cells. The process involves antigen-presenting cells activating T cells, leading to a delayed response. Choices A, B, and C involve different mechanisms and are not mediated by T cells. Type I is mediated by IgE antibodies, Type II involves antibody-mediated cell destruction, and Type III involves immune complex deposition. Therefore, Type IV is the only hypersensitivity type directly mediated by T cells.
What is the primary advantage of Toll-like receptors (TLRs)?
- A. They are highly specific to individual pathogens
- B. They recognize common molecular patterns shared by groups of microbes
- C. They activate B cell antibody production
- D. They require antigen presentation to function
Correct Answer: B
Rationale: The correct answer is B because Toll-like receptors (TLRs) recognize common molecular patterns shared by groups of microbes, allowing for rapid detection of a wide range of pathogens. This recognition triggers immune responses without the need for prior exposure to the specific pathogen. The other choices are incorrect because:
A: TLRs are not highly specific to individual pathogens but rather recognize common patterns.
C: TLRs do not directly activate B cell antibody production; they initiate immune responses by activating various immune cells.
D: TLRs do not require antigen presentation to function; they directly recognize microbial patterns.
Which of the following are not typically found within secondary lymphoid tissues?
- A. naïve lymphocytes
- B. Hematopoietic stem cells
- C. Dendritic cells
- D. Antigen
Correct Answer: B
Rationale: Correct Answer: B - Hematopoietic stem cells are not typically found within secondary lymphoid tissues because they are located in the bone marrow where they give rise to various blood cells. In contrast, secondary lymphoid tissues like lymph nodes and spleen primarily consist of mature immune cells and support immune responses. Naïve lymphocytes (A), dendritic cells (C), and antigens (D) are commonly found in secondary lymphoid tissues as they play crucial roles in the immune response.