Pathophysiology Practice Questions Related

Review Pathophysiology Practice Questions related questions and content

What is a cause of the crystallization within the synovial fluid of the joint affected by gouty arthritis?

  • A. Destruction of proteoglycans
  • B. Underexcretion of uric acid
  • C. Overexcretion of uric acid
  • D. Increased absorption of uric acid
Correct Answer: B

Rationale: The correct answer is B: Underexcretion of uric acid. Gouty arthritis is primarily caused by the underexcretion of uric acid, leading to its accumulation in joints and subsequent crystallization. Choices A, C, and D are incorrect as they do not directly relate to the pathophysiology of gout. Destruction of proteoglycans, overexcretion of uric acid, and increased absorption of uric acid are not primary causes of gouty arthritis.