Nokea
What is a primary characteristic of modern immunology?
- A. It relies solely on innate immunity concepts
- B. It builds on the pioneering work of Jenner, Pasteur, and others
- C. It focuses exclusively on tissue healing
- D. It is an ancient field of study with minimal current advancements
Correct Answer: B
Rationale: The correct answer is B because modern immunology indeed builds on the groundbreaking contributions of scientists like Jenner and Pasteur. Their work laid the foundation for understanding concepts like vaccination and immune responses. Choice A is incorrect because modern immunology encompasses both innate and adaptive immunity. Choice C is incorrect as immunology extends beyond tissue healing to include immune responses to pathogens and self-cells. Choice D is incorrect as immunology is a rapidly evolving field with significant advancements in understanding immune mechanisms and developing new treatments.
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Which of the following statements is incorrect?
- A. The gut microbiome composition in obese individuals is altered and shows overrepresentation of less beneficial species
- B. Fecal transplants have been used to treat Clostridium difficile infections
- C. Crohn's disease is considered a disease caused by loss of tolerance to the gut microbiota
- D. The bacterial type III secretion system is used by species of the gut microbiota to inject effector proteins into intestinal epithelial cells and invade them, as observed in Crohn's disease
Correct Answer: D
Rationale: The correct answer is D because the statement incorrectly implies that the bacterial type III secretion system is used by gut microbiota to invade intestinal epithelial cells in Crohn's disease. In reality, Crohn's disease is not directly caused by invasion of gut microbiota into intestinal cells; it is a complex autoimmune condition. The gut microbiota dysbiosis is associated with Crohn's disease, but invasion of epithelial cells is not the primary mechanism. Choices A, B, and C are correct: A highlights the altered microbiome in obesity, B discusses the use of fecal transplants for C. difficile infections, and C mentions Crohn's disease related to issues with gut microbiota tolerance.
Follicular dendritic cells
- A. Are found in the blood
- B. Are important for sustaining antibody responses
- C. Represent a HAART-resistant reservoir of virus in HIV-infected individuals
- D. Can activate naïve T lymphocytes
Correct Answer: E
Rationale: I'm sorry, but the question you provided does not have option E listed. Could you please provide the correct options for the question so I can assist you with a detailed explanation of the correct answer and why the other choices are incorrect?
Which mutated tumor suppressor gene is most likely to contribute to many types of cancer, including bladder, breast, colorectal, and lung?
- A. p53
- B. APC
- C. BRCA1
- D. BRCA2
Correct Answer: A
Rationale: The p53 gene is a critical tumor suppressor gene involved in preventing cancer by regulating the cell cycle and initiating apoptosis. Mutations in this gene are associated with many types of cancer.
The nurse is caring for a patient who just returned from surgical decompression of the carpal tunnel. Which finding requires the nurse's immediate action?
- A. The patient's fingers swollen and warm.
- B. The patient complains of generalized pain 5/10.
- C. The capillary refill time is 8 seconds.
- D. The patient's fingers are pink and cool bilaterally.
Correct Answer: C
Rationale: The correct answer is C because a capillary refill time of 8 seconds indicates poor perfusion, which could be a sign of compromised blood flow to the fingers post-surgical decompression. This finding requires immediate action to prevent complications such as ischemia or impaired wound healing.
A: Swollen and warm fingers are expected after surgery due to inflammation.
B: Generalized pain can be managed with appropriate pain relief measures and is not an immediate concern post-surgery.
D: Pink and cool fingers indicate adequate perfusion and are normal findings post-surgery.
What is included in the humoral immune response?
- A. Surveillance for malignant cell changes
- B. Production of antigen-specific immunoglobulins
- C. Direct attack of antigens by activated B lymphocytes
- D. Releasing cytokines responsible for destruction of antigens
Correct Answer: B
Rationale: The humoral immune response involves the production of antigen-specific antibodies (immunoglobulins) by B cells, which neutralize pathogens.