Nokea
What is ONE gene mutation typically associated with Marfan’s syndrome?
- A. FBN1
- B. ACTA2
- C. SIX2
- D. TGFBR2
Correct Answer: A
Rationale: The FBN1 mutation is the most commonly identified genetic mutation associated with Marfan's syndrome.
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Patients who have undergone surgery entailing the use of cardiopulmonary bypass should be watched carefully for
- A. epilepsy disabilities
- B. learning disabilities
- C. anemia
- D. arrhythmias
Correct Answer: D
Rationale: Arrhythmias are a common complication after cardiopulmonary bypass surgery.
Evidence of increased pulmonary flow is associated with:
- A. Coarctation of the aorta
- B. Fallot's tetralogy
- C. Pneumocystis infection
- D. Ventricular septal defect
Correct Answer: D
Rationale: A ventricular septal defect (VSD) leads to increased pulmonary blood flow due to left-to-right shunting, resulting in pulmonary congestion.
During play, a toddler with a history of tetralogy of Fallot (TOF) might assume which position?
- A. Sitting
- B. Supine
- C. Squatting
- D. Standing
Correct Answer: C
Rationale: Squatting naturally increases SVR by occluding venous return from the lower extremities, thereby increasing pulmonary blood flow.
What are FIVE indications for surgical intervention in infective endocarditis?
- A. Heart block
- B. Abscess
- C. Valve dysfunction causing heart failure
- D. Large mobile vegetation
Correct Answer: A
Rationale: These are typical indications for surgery when complications of infective endocarditis progress to life-threatening stages.
One of the following is a characteristic physical finding in patients with an ASD
- A. a right precordial bulge
- B. a fixed splitting of the second heart sound
- C. a systolic ejection heart murmur
- D. a short, mild left mid-diastolic murmur
Correct Answer: B
Rationale: Fixed splitting of the second heart sound is a hallmark of an atrial septal defect.