ATI Pharmacology Test Bank Related

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What is the most life threatening adverse reaction while taking Omeprazole?

  • A. Chest pain
  • B. Constipation
  • C. Clostridium Difficile Associated Diarrhea
  • D. Acute interstitial nephritis
Correct Answer: D

Rationale: Acute interstitial nephritis is a rare but serious adverse reaction associated with omeprazole. It is characterized by inflammation of the kidney's interstitial tissue and can lead to kidney dysfunction. Symptoms may include fever, rash, eosinophilia, and impaired renal function. If left untreated, acute interstitial nephritis can progress to acute kidney injury and potentially be life-threatening. Therefore, it is essential to promptly recognize and manage this adverse reaction when taking omeprazole.