What is the role of pepsin in digestion?
- A. Digesting carbohydrates
- B. Digesting fats
- C. Digesting proteins
- D. Digesting nucleic acids
Correct Answer: C
Rationale: The correct answer is C: Digesting proteins. Pepsin is a digestive enzyme produced in the stomach that specifically breaks down proteins into smaller peptides. It works optimally in acidic environments, aiding in the digestion of proteins consumed in the diet. The other choices are incorrect because pepsin does not play a role in digesting carbohydrates (A), fats (B), or nucleic acids (D). Carbohydrates are primarily broken down by enzymes like amylase, fats by lipase, and nucleic acids by nucleases. Thus, pepsin's main function is to digest proteins in the stomach.
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Primary carcinoma is least common in:
- A. esophagus
- B. stomach
- C. small intestine
- D. colon
Correct Answer: C
Rationale: The correct answer is C: small intestine. Primary carcinoma is least common in the small intestine compared to the other choices. This is because the small intestine has a lower incidence of cancer compared to the esophagus, stomach, and colon. Factors contributing to this lower incidence include less exposure to carcinogens, a relatively smaller surface area, and less common inflammatory conditions that can lead to cancer development. Additionally, the small intestine has a more rapid turnover of cells, reducing the likelihood of cancerous mutations accumulating. Therefore, the small intestine is the least common site for primary carcinoma among the options provided.
Which patient is at highest risk for having a gastric ulcer?
- A. 55-year-old female, smoker, with nausea and vomiting
- B. 45-year-old female admitted for illicit drug detoxification
- C. 37-year-old male, smoker, who fell while looking for a job
- D. 27-year old male who is being divorced and has back pain
Correct Answer: A
Rationale: The correct answer is A because a 55-year-old female who is a smoker and experiencing symptoms of nausea and vomiting has multiple risk factors for developing a gastric ulcer. Smoking and older age are established risk factors for gastric ulcers. Nausea and vomiting can be indicative of underlying gastrointestinal issues.
Choice B is less likely as illicit drug use typically does not directly increase the risk of gastric ulcers.
Choice C is less likely as the male falling while looking for a job does not directly relate to gastric ulcer development.
Choice D is less likely as divorce and back pain are not direct risk factors for gastric ulcers.
Which information will the nurse include when teaching a patient with peptic ulcer disease about the effect of ranitidine (Zantac)?
- A. Ranitidine absorbs the excess gastric acid.
- B. Ranitidine decreases gastric acid secretion.
- C. Ranitidine constricts the blood vessels near the ulcer.
- D. Ranitidine covers the ulcer with a protective material.
Correct Answer: B
Rationale: Rationale: Ranitidine is an H2 receptor antagonist that works by blocking the action of histamine on the stomach cells, thereby reducing gastric acid secretion. This helps in healing and preventing further damage to the ulcer. Option A is incorrect as ranitidine doesn't absorb excess gastric acid; it reduces its production. Option C is incorrect as ranitidine doesn't constrict blood vessels. Option D is incorrect as ranitidine doesn't cover the ulcer but rather decreases acid secretion to promote healing.
A nurse is assessing a client who has an obstruction of the common bile duct resulting from chronic cholecystitis. Which of the following findings should the nurse expect?
- A. Fatty stools
- B. Straw-colored urine
- C. Tenderness in the left upper abdomen
- D. Ecchymosis of the extremities
Correct Answer: A
Rationale: The correct answer is A: Fatty stools. Common bile duct obstruction leads to inadequate bile flow into the intestines, resulting in malabsorption of fats. This causes fatty stools due to the presence of undigested fats. Straw-colored urine (B) is a normal finding. Tenderness in the left upper abdomen (C) is more indicative of splenic issues. Ecchymosis of the extremities (D) is unrelated to common bile duct obstruction.
GIT hormones with a major effect on the stomach include the following except:
- A. Gastrin
- B. Secretin
- C. GIP
- D. Neurotensin
Correct Answer: B
Rationale: Secretin is the correct answer because it is not a hormone that directly affects the stomach. Gastrin stimulates gastric acid secretion, GIP enhances insulin release, and neurotensin regulates gastric motility. Secretin primarily targets the pancreas and liver, stimulating the release of bicarbonate-rich pancreatic juice. This hormone does not have a direct major effect on the stomach like the other options. Therefore, Secretin is the exception among the listed GIT hormones affecting the stomach.