Nokea
What type of cytokine will attract neutrophils and monocytes to remove debris?
- A. Lymphokines
- B. Cytotoxic T cells
- C. Suppressor T cells
- D. Regulator T cells
Correct Answer: A
Rationale: Lymphokines, a type of cytokine, attract cells when they detect antigens and direct B-cell lymphocytes to multiply and mature. Cytotoxic T cells bind to invading cells, destroy the targeted invader by altering their cellular membrane and intracellular environment, and stimulate the release of chemicals called lymphokines. Suppressor T cells limit or turn off the immune response in the absence of continued antigenic stimulation. Regulator T cells are made up of helper and suppressor cells.
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A client who is a teenager has been brought to the clinic by the parent and is suspected of having an immune system disorder. What tests would the nurse expect to be ordered for this young client?
- A. Cerebral spinal fluids aspiration
- B. Sedimentary rate
- C. Complete blood count with differential
- D. Complete chemistry panel
Correct Answer: C
Rationale: Laboratory tests are used to identify immune system disorders. They usually include a complete blood count with differential. Protein electrophoresis screens for diseases associated with a deficiency or excess of immunoglobulins. T-cell and B-cell assays (or counts) and the enzyme-linked immunosorbent assay may be performed. The other options are not diagnostic of immune disorders.
A client's immune system has the ability to protect itself from external invaders. What type of immune function is present when this occurs?
- A. Immunosuppression
- B. Immunocompetence
- C. An immune response
- D. Immune incompatibility
Correct Answer: B
Rationale: The immune system is a collection of specialized white blood cells and lymphoid tissues that maintain immunocompetence, the ability to cooperatively protect a person from external invaders and the body's own altered cells. Immunosuppression is the opposite and the white blood cells and lymphoid tissue are not able to protect a person from external invaders. An immune response, primarily involves the lymphocytes that are located in blood and lymphoid tissue. Immune incompatibility is not relevant in this situation.
The nurse is obtaining medication history information from a client with Crohn's disease. What medication would the nurse include when asking what medications the client has taken for suppression of the inflammatory and immune response?
- A. Nonsteroidal anti-inflammatory
- B. Angiotensin-converting enzyme inhibitors (ACE-I)
- C. Diuretics
- D. Corticosteroids
Correct Answer: D
Rationale: The nurse obtains a history of immunizations, recent and past infectious diseases, and recent exposure to infectious diseases. The nurse reviews the client's drug history because certain drugs, such as corticosteroids, suppress the inflammatory and immune responses. Nonsteroidal anti-inflammatory medication does not suppress the inflammatory and immune responses of Crohn's disease. An ACE-I prevents the conversion of angiotensin I to angiotensin II and does not suppress the inflammatory or immune response. Diuretics also do not suppress the immune response but help reduce excess fluid from the kidneys.
The nurse is administering a skin test for detection of exposure to tuberculosis. How would the nurse determine if the client was exposed to tuberculosis?
- A. The client will have a productive cough.
- B. The injection area swells if the client has developed antibodies against the antigen.
- C. The injection area will become painful with induration if the client has antibodies against the antigen.
- D. The injection area will break out in a fine macular rash.
Correct Answer: B
Rationale: The injection area swells if the client has developed antibodies against the antigen. The client is not necessarily actively infectious if the test results are positive. Although a productive cough is one of the symptoms of active tuberculosis, it may also indicate other diseases and disorders. The area should not be painful, and the client should not break out with a rash.
A child is brought to the clinic with a rash and is subsequently diagnosed with measles. The parent reports also having had measles as a young child. What type of immunity to measles develops after the initial infection?
- A. Naturally acquired active immunity
- B. Artificially acquired active immunity
- C. Naturally acquired passive immunity
- D. Artificially acquired passive immunity
Correct Answer: A
Rationale: Immunity to measles that develops after the initial infection is an example of naturally acquired active immunity. Artificially acquired active immunity results from the administration of a killed or weakened microorganism or toxoid (attenuated toxin), whereas passive immunity develops when ready-made antibodies are given to a susceptible client.