When taken with aminoglycosides, platinum chemotherapy or cyclosporin increase the risk of
- A. Kidney damage
- B. Ototoxicity
Correct Answer: A
Rationale: Platinum chemotherapy (e.g., cisplatin) and cyclosporin both potentiate aminoglycoside nephrotoxicity, increasing kidney damage risk.
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A nurse is caring for a school-age child who has a new prescription for Atomoxetine. The nurse should monitor the client for which of the following adverse effects of this medication?
- A. Kidney toxicity
- B. Liver damage
- C. Seizure activity
- D. Adrenal insufficiency
Correct Answer: B
Rationale: Atomoxetine can cause liver damage , a rare but serious effect to monitor.
An important concept taught by the nurse when providing medication teaching is the need to provide a complete list of medications taken to health care providers to avoid what?
- A. Spending large amounts of money on medications
- B. Allergic reactions to medications
- C. Drug-drug interactions
- D. Critical concentrations of medications in the body
Correct Answer: C
Rationale: It is important that all health care providers have a complete list of the patients medications to avoid drug-drug interactions caused by one provider ordering a medication, unaware of another medication the patient is taking that could interact with the new prescription. Using the same pharmacist for all prescriptions will also help to prevent this from happening. Informing the provider of all medications taken will not reduce costs of medications, which is best accomplished by requesting generic medications. Allergies should be disclosed to all health care providers as well, but this is not why it is important to provide a complete list of medications taken. Critical concentrations are desirable because that is the amount of drug needed to cause a therapeutic effect, or, in other words, to have the effect the drug is prescribed for.
This drug is a respiratory stimulant:
- A. Doxapram
- B. Promethazine
- C. Dornase α
- D. Oxygen
Correct Answer: A
Rationale: Doxapram stimulates breathing by acting on the respiratory center in the brainstem.
A 19-year-old male was started on risperidone. Monitoring for risperidone includes observing for common side effects, including:
- A. Bradykinesia, akathisia, and agitation
- B. Excessive weight gain
- C. Hypertension
- D. Potentially fatal agranulocytosis
Correct Answer: A
Rationale: Risperidone frequently causes movement disorders like bradykinesia and akathisia.
The nurse is reviewing the results of the patient's laboratory tests. What must the nurse keep in mind when reviewing these results related to medication administration?
- A. The patient's emotional response to the disease process
- B. The timing of the last dose of medication relative to when blood was drawn
- C. The possibility of a drug-laboratory test interaction
- D. A change in the body's responses or actions related to the drug
Correct Answer: C
Rationale: The body works through a series of chemical reactions. Because of this, administration of a particular drug may alter results of tests that are done on various chemical levels or reactions as part of a diagnostic study. This drug-laboratory test interaction is caused by the drug being given and not necessarily by a change in the body's responses or actions. The patient's emotional response or timing of the last dose is not important in drug-laboratory interactions.
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