Nokea
Which antiarrhythmic medication is primarily used for atrial fibrillation?
- A. Propranolol
- B. Amiodarone
- C. Digoxin
- D. Verapamil
Correct Answer: B
Rationale: Amiodarone is widely used for atrial fibrillation due to its broad-spectrum antiarrhythmic effects across multiple classes.
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What is the fraction of unchanged drug reaching the systemic circulation?
- A. Elimination
- B. Bioavailability
- C. Metabolism
- D. Drug displacement
Correct Answer: B
Rationale: Bioavailability is defined as the fraction of unchanged drug that reaches systemic circulation, a key pharmacokinetic parameter.
Anti-inflammatory action of glucocorticoids is determined by:
- A. Inhibition of phospholipase A2
- B. Activation of phospholipase A2
- C. Inhibition of cyclooxygenase type-1
- D. Inhibition of cyclooxygenase type-2
Correct Answer: A
Rationale: Glucocorticoids inhibit phospholipase A2, reducing the production of inflammatory mediators like prostaglandins.
Which statement(s) will be included when planning patient teaching regarding drug names?(Select one that does not apply.)
- A. Most drug companies place their products on the market under generic names
- B. The official name is the name under which the drug is listed by the US Food and Drug Administration (FDA)
- C. Brand names are easier to pronounce, spell, and remember
- D. The first letter of the generic name is not capitalized
Correct Answer: A
Rationale: The official name is listed by the FDA , brand names are easier for patients , and generic names are not capitalized . Most drugs are marketed under brand names, not generic.
Phil is starting treatment with febuxostat (Uloric). Education of patients starting febuxostat includes:
- A. Gout may worsen with therapy
- B. Febuxostat may cause severe diarrhea
- C. He should consume a high-calcium diet
- D. He will need frequent CBC monitoring
Correct Answer: A
Rationale: Febuxostat can initially worsen gout as uric acid mobilizes; diarrhea or calcium aren't emphasized.
Effects of glucagon are:
- A. Positive inotropic and chronotropic effects
- B. Negative inotropic and chronotropic effects
- C. Inhibition of Gs protein and decrease of CAMP
- D. Activation of Gq and accumulation of Inositol triphosphate
Correct Answer: A
Rationale: Glucagon has positive inotropic and chronotropic effects on the heart, increasing contractility and rate.