Despite good blood pressure control, an NP might change a patient's drug from an angiotensin-converting enzyme (ACE) inhibitor to an angiotensin II receptor blocker (ARB) because the ARB:
- A. Is stronger than the ACE inhibitor
- B. Does not produce a dry, hacky cough
- C. Has no effect on the renal system
- D. Reduces sodium and water retention
Correct Answer: B
Rationale: ARBs lack the cough side effect common with ACE inhibitors.
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While studying for the test, the nursing student encounters the following drug: papaverine (Pavabid). What does the nursing student identify the name Pavabid as?
- A. The generic name
- B. The chemical name
- C. The brand name
- D. The chemical and generic name
Correct Answer: C
Rationale: Several clues indicate the brand name including capitalization of the first letter in the name and in parentheses. Generic names are not capitalized; chemical names are descriptions of the chemistry of the medication resulting in complicated names.
Piroxicam has a particularly long half-life (50 hours) as it undergoes enterohepatic recycling.
- A. TRUE
- B. FALSE
Correct Answer: A
Rationale: Piroxicam's long half-life is due to enterohepatic recycling, prolonging its presence in the body.
Insulin medications are not administered per os because
- A. Are poorly absorbed in GI truct
- B. They are breaksdown by the action of dygestive enzymes
- C. Increase glucose absorbtion
Correct Answer: B
Rationale: Insulin is a peptide broken down by digestive enzymes, rendering oral administration ineffective.
The following drugs are excreted in the bile except:
- A. Erythromycin
- B. Novobiocin
- C. Chloramphenicol
- D. Rifampicin
Correct Answer: C
Rationale: Chloramphenicol is primarily excreted via the kidneys, not bile.
Taking which drug with food maximizes it bioavailability?
- A. Donepezil
- B. Galantamine
- C. Rivastigmine
- D. Memantine
Correct Answer: C
Rationale: Rivastigmine's bioavailability is maximized with food, reducing GI side effects.