A 27-year-old male is admitted to the Emergency Department (ED) after a serious motorcycle accident. The patient has a head injury, abrasions covering the left side of his body, a broken left femur, and internal injuries that are not fully assessed at this time. He is transferred from the ED to the ICU. The nurse who is going to care for this patient in the ICU knows that one of their most important responsibilities in regard to drug therapy is what?
- A. Support vital functions
- B. Continue curative treatment
- C. Institute life-saving treatment
- D. Monitor the patient's response
Correct Answer: D
Rationale: Monitoring drug response ensures timely adjustments in critical care, optimizing therapy amidst multiple injuries.
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A patient is ordered to receive a subcutaneous injection of heparin twice a day. When administering this drug to the patient, which of the following would be most important for the nurse to do to minimize tissue damage?
- A. Insert the needle at the appropriate angle.
- B. Select the needle length based on the patient's weight.
- C. Ensure that there is no hair on the injection site.
- D. Rotate the injection site regularly.
Correct Answer: D
Rationale: The nurse should rotate the injection sites to minimize the damage caused to the tissue. Inserting the needle at the proper angle and selecting the needle length based on the patient's weight will not significantly help in minimizing tissue damage if the same site is repeatedly injected. It is not necessary to avoid injection sites that have hair as long as the drug is administered in the upper arms, the upper abdomen, and the upper back.
While studying for the test, the nursing student encounters the following drug: papaverine (Pavabid). What does the nursing student identify the name Pavabid as?
- A. The generic name
- B. The chemical name
- C. The brand name
- D. The chemical and generic name
Correct Answer: C
Rationale: Several clues indicate the brand name including capitalization of the first letter in the name and in parentheses. Generic names are not capitalized; chemical names are descriptions of the chemistry of the medication resulting in complicated names.
What is the fraction of unchanged drug reaching the systemic circulation?
- A. Elimination
- B. Bioavailability
- C. Metabolism
- D. Drug displacement
Correct Answer: B
Rationale: Bioavailability is defined as the fraction of unchanged drug that reaches systemic circulation, a key pharmacokinetic parameter.
While providing medications to clients on the cardiac unit, the nurse anticipates that hydralazine hydrochloride and isosorbide dinitrate (BiDil) would most likely be prescribed for which of the following clients?
- A. A 48-year-old Caucasian male diagnosed with atrial fibrillation
- B. A 55-year-old African American female diagnosed with hypertension
- C. A 63-year-old Caucasian female diagnosed with sick sinus syndrome
- D. A 64-year-old African American male diagnosed with heart failure
Correct Answer: D
Rationale: BiDil (hydralazine/isosorbide) is FDA-approved specifically for heart failure in African Americans , showing improved outcomes in this population.
Levetiracetam has known drug interactions with:
- A. Combined oral contraceptives
- B. Carbamazepine
- C. Warfarin
- D. Few, if any, drugs
Correct Answer: D
Rationale: Levetiracetam has minimal drug interactions due to its unique metabolism.
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