Nokea
Which bacterium is known for producing a green pigment called pyocyanin?
- A. Staphylococcus aureus
- B. Pseudomonas aeruginosa
- C. Escherichia coli
- D. Clostridium difficile
Correct Answer: B
Rationale: The correct answer is B: Pseudomonas aeruginosa. P. aeruginosa is known for producing pyocyanin, a green pigment. This bacterium is commonly associated with infections in immunocompromised individuals. Staphylococcus aureus (choice A) produces golden-yellow pigments, not green. Escherichia coli (choice C) and Clostridium difficile (choice D) do not produce pyocyanin. Therefore, the correct choice is B based on the characteristic pigment produced by Pseudomonas aeruginosa.
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A 23-year old medical student arrives in the student health clinic complaining of difficult in swallowing, sore throat, and chills. Upon examination, she is found to be running a fever and has white patches on her tonsils. A throat swab is positive for streptococcus pyogenes (group A). A diagnosis of acute pharyngitis is made. Her past medical history is unremarkable except an anaphylactic reaction to cefaclor two years ago. Which of the following would be a safe alternative for treating?
- A. Amoxicillin
- B. Meropenem
- C. Cephalexin
- D. Clindamycin
Correct Answer: D
Rationale: The correct answer is D: Clindamycin. Clindamycin is a lincosamide antibiotic that is safe to use in patients with a history of anaphylaxis to beta-lactam antibiotics like cefaclor. Clindamycin is effective against streptococcus pyogenes and is a suitable alternative in this case. Amoxicillin (choice A) is a beta-lactam antibiotic similar to cefaclor and may cause a cross-reactive allergic reaction. Meropenem (choice B) is a carbapenem antibiotic and not typically used for acute pharyngitis. Cephalexin (choice C) is a cephalosporin antibiotic and may also cause cross-reactivity in patients with a history of anaphylaxis to cefaclor.
Mesophylic bacteria are with temperature optimum:
- A. 25-37 °C
- B. 55-65 °C
- C. 15-18 °C
- D. 38-45 °C
Correct Answer: A
Rationale: The correct answer is A (25-37 °C) because mesophilic bacteria thrive best at moderate temperatures typical of most environments, making 25-37 °C their optimum range. This range allows for optimal enzyme activity and growth. Choice B (55-65 °C) is incorrect as it is more suitable for thermophilic bacteria. Choice C (15-18 °C) is too low for mesophiles to thrive efficiently. Choice D (38-45 °C) is too high and is more suitable for thermophiles. Ultimately, the correct answer aligns with the typical temperature range where mesophilic bacteria are most active and abundant.
Which scientist is most responsible for ending the controversy about spontaneous generation?
- A. John Needham
- B. Joseph Lister
- C. Louis Pasteur
- D. Robert Koch
Correct Answer: C
Rationale: The correct answer is C: Louis Pasteur. He conducted experiments that definitively disproved the theory of spontaneous generation through his famous swan-neck flask experiment. By showing that microorganisms only appeared in the broth when exposed to air, Pasteur demonstrated that they did not arise spontaneously. John Needham's experiments were inconclusive, Joseph Lister is known for his contributions to antiseptic surgery, and Robert Koch is credited with developing Koch's postulates for identifying the causative agents of diseases, but neither of them directly contributed to ending the controversy about spontaneous generation.
Which of the following bacteria produce endotoxins that can lead to septic shock?
- A. Staphylococcus aureus
- B. Escherichia coli
- C. Pseudomonas aeruginosa
- D. All of the above
Correct Answer: D
Rationale: The correct answer is D because all three bacteria listed (Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa) can produce endotoxins that can lead to septic shock. Endotoxins are lipopolysaccharides found in the outer membrane of Gram-negative bacteria like E. coli and P. aeruginosa. Staphylococcus aureus, a Gram-positive bacterium, can also produce endotoxins called superantigens that can trigger a massive immune response leading to septic shock. Therefore, all of the above choices are correct. Choices A, B, and C alone are incorrect because they do not account for the fact that all three bacteria listed produce endotoxins that can cause septic shock.
What is the role of bacterial ribosomes?
- A. Protein synthesis
- B. DNA replication
- C. Flagella formation
- D. Toxin production
Correct Answer: A
Rationale: The correct answer is A: Protein synthesis. Bacterial ribosomes are responsible for translating mRNA into proteins through a process called translation. This is a crucial step in gene expression, where amino acids are assembled into polypeptide chains. Choice B (DNA replication) is incorrect because ribosomes are not involved in DNA replication. Choice C (Flagella formation) is incorrect as ribosomes do not play a direct role in flagella formation. Choice D (Toxin production) is incorrect as ribosomes are not directly involved in producing toxins.