Which chromosomal abnormality is often characteristic of infantile ALL?
- A. t(4;11)
- B. t(12;21)
- C. t(9;22)
- D. t(1;19)
Correct Answer: A
Rationale: The t(4;11) translocation is commonly found in infantile ALL and is associated with a poor prognosis.
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Laboratory studies indicate a client's blood pressure level is 185mg/dl. Two hours have passed since the client ate breakfast. Which test would yield the most occlusive diagnostic information about the client's glucose utilization?
- A. A fasting blood glucose test
- B. A test of serum glycosylated hemoglobin (HbA1c)
- C. A 6-hour glucose tolerance test
- D. A test for urine ketones
Correct Answer: C
Rationale: A 6-hour glucose tolerance test would yield the most occlusive diagnostic information about the client's glucose utilization in this case. The elevated blood pressure level of 185 mg/dL two hours after breakfast indicates poor glucose regulation. A glucose tolerance test involves monitoring the client's blood glucose levels over a period of time after ingesting a glucose solution. This test provides a comprehensive assessment of how the body processes glucose, revealing any abnormalities in glucose metabolism beyond fasting levels, such as postprandial (after-meal) glucose spikes and prolonged hyperglycemia. This can help identify conditions like insulin resistance, impaired glucose tolerance, or diabetes, which may not be evident from a fasting blood glucose test alone. Glycosylated hemoglobin (HbA1c) reflects average blood sugar levels over the past 2-3 months and would not provide immediate information about the client's current glucose metabolism. Urine ketones
Which of the following chromosomal abnormalities of childhood ALL carries the highest risk of relapse despite intensive chemotherapy?
- A. t(9;22)
- B. t(4;11)
- C. hypodiploidy
- D. t(1;19)
Correct Answer: A
Rationale: The Philadelphia chromosome (t(9;22)) is associated with a high risk of relapse in ALL.
The nurse is instructed to perform preoperative preparation for the management of a client with malignant tumors. Which of the ff is the most important factor of the nursing management plan?
- A. Insertion of an ostomy pouch
- B. Assessing the symptoms of peritonitis
- C. Maintaining the integrity of the urinary
- D. Insertion of a nasogastric tube diversion procedure
Correct Answer: B
Rationale: Peritonitis is a serious and potentially life-threatening condition that can occur as a complication of malignant tumors. It is characterized by inflammation of the lining of the abdomen and can result in severe abdominal pain, tenderness, fever, and other symptoms. Prompt assessment of peritonitis symptoms is crucial for early detection and intervention to prevent further complications and improve patient outcomes. Assessing for peritonitis symptoms should be the priority in the nursing management plan to ensure timely and appropriate care for the client with malignant tumors.
When caring for a child that has undergone a tonsillectomy, the nurse should do which of the following?
- A. Observe for continuous swallowing.
- B. Encourage gargling with warm saline water.
- C. Apply warm compresses to the throat.
- D. Apply cold compresses to the throat.
Correct Answer: A
Rationale: When caring for a child that has undergone a tonsillectomy, the nurse should observe for continuous swallowing. Continuous swallowing may indicate bleeding, and it is important to monitor for this postoperatively as it can be a sign of hemorrhage, which is a potential complication following a tonsillectomy. Encouraging the child to take sips of clear fluids can help in assessing if there is bleeding. Observing for any signs of bleeding, such as frequent swallowing, along with monitoring vital signs and overall assessment, is crucial during the initial postoperative period.
HIV antibody testing procedures using a finger stick or venipuncture to obtain whole blood, plasma, or serum, and tests using oral fluid were approved. All the following regarding this test are true EXCEPT
- A. they are simple and accurate as to render the likelihood of an erroneous result by the user negligible
- B. a positive result does not need confirmation by Western blot analysis or immunofluorescence assay
- C. they allow women who have not been tested or are unaware of their HIV status to reduce the risk of mother-to-child transmission of antiretroviral therapy implementation
- D. they significantly reduce the risk of mother-to-child transmission
Correct Answer: B
Rationale: A positive result from rapid HIV tests still requires confirmation with more specific tests like Western blot or immunofluorescence assay.