Which factor has been shown to increase the risk of development of atherosclerosis?
Correct Answer: A
Rationale: The correct answer is A: Menopause. Menopause is associated with an increased risk of atherosclerosis due to hormonal changes that affect lipid profiles and vascular health. Conversely, B: Age older than 35 is not necessarily a risk factor for atherosclerosis on its own, though atherosclerosis risk does generally increase with age. C: Increased levels of arachidonic acid is not specifically linked to atherosclerosis; it's a fatty acid that can be both beneficial and harmful to health depending on its metabolic pathway. D: Elevated HDL cholesterol is actually beneficial rather than harmful because HDL cholesterol is known as 'good' cholesterol that helps to reduce the risk of heart disease and atherosclerosis.