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Which mode of action has insulin in fatty cells?
- A. Decrease glycerol synthesis
- B. Increase synthesis of triglycerides
- C. Decrease fatty acid synthesis
Correct Answer: B
Rationale: Insulin promotes triglyceride synthesis in fat cells by enhancing glucose uptake and lipogenesis.
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The following drug is not secreted in bile
- A. Penicillin
- B. Phenolphthalein
- C. Novobiocin
- D. Erythromycin
Correct Answer: A
Rationale: Penicillin is excreted via kidneys; others are secreted in bile.
Being competent in the use of information technology in clinical practice is expected in professional nurses. Advanced practice competence includes the ability to:
- A. Search for information using the most common search engines
- B. Serve as content experts in developing, implementing, and evaluating information systems
- C. Write programs to assure the integrity of health information
- D. Use information technology to prescribe drugs
Correct Answer: B
Rationale: Advanced practice nurses contribute expertise in IT system development and evaluation.
A patient with Type 2 diabetes mellitus begins gaining weight after several months of therapy with an oral antidiabetic agent. A complete workup indicates edema and other signs and symptoms of heart failure. Which of the following antidiabetic drug or group was the most likely cause?
- A. Acarbose
- B. Biguanides
- C. Glitazones (thiazolidinediones, such as rosiglitazone)
- D. Metformin
Correct Answer: C
Rationale: Glitazones like rosiglitazone can cause fluid retention and weight gain, increasing the risk of heart failure.
Cholinergic blockers are used to:
- A. Counteract the extrapyramidal symptoms (EPS) effects of phenothiazines
- B. Control tremors and relax smooth muscle in Parkinson's disease
- C. Inhibit the muscarinic action of ACh on bladder muscle
- D. All of the above
Correct Answer: D
Rationale: Cholinergic blockers address EPS, Parkinson's symptoms, and bladder overactivity.
A patient arrives in the emergency department in an acute state of alcohol intoxication and reports chronic consumption of several six packs of beer every day for the past year. The nurse anticipates administering which medication or treatment?
- A. Chlordiazepoxide (Librium)
- B. Disulfiram (Antabuse)
- C. Gastric lavage
- D. Vasoconstrictors
Correct Answer: A
Rationale: Chlordiazepoxide prevents alcohol withdrawal symptoms; disulfiram is post-detox. To prevent acute withdrawal and delirium tremens, a long-acting benzodiazepine, such as chlordiazepoxide, is given.