Nokea
Which of the following adverse effects of chronic high-dose prednisone administration represents a mineralocorticoid effect?
- A. Buffalo hump
- B. Easy bruising
- C. Edema
- D. Moon facies
Correct Answer: C
Rationale: Edema is a mineralocorticoid effect of prednisone due to sodium and water retention.
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Which of the following drugs are mucolytics?
- A. Diphenhydramine
- B. Carbocisteine and mecysteine
- C. Methadone or diamorphine
- D. Atropine
Correct Answer: B
Rationale: Carbocisteine and mecysteine break mucus disulfide bonds, acting as mucolytics.
John has clonidine, a centrally acting adrenergic blocker, prescribed for his hypertension. He should:
- A. Not miss a dose or stop taking the drug because of potential rebound hypertension
- B. Increase fiber in the diet to treat any diarrhea that may occur
- C. Reduce fluid intake to less than 2 liters per day to prevent fluid retention
- D. Avoid sitting for long periods, as this can lead to deep vein thrombosis
Correct Answer: A
Rationale: Clonidine withdrawal can cause rebound hypertension, making adherence critical.
Methanol causes blindness due to its
- A. Hypersensitivity reactions
- B. Conjugated products
- C. Idiosyncratic reaction
- D. Oxidative products
Correct Answer: D
Rationale: Methanol's metabolite, formic acid (oxidative product), damages the optic nerve, causing blindness.
All of the following are protein bound except:
- A. Propranolol
- B. Atenolol
- C. Phenylbutazone
- D. Warfarin
Correct Answer: B
Rationale: Atenolol has low protein binding; others bind extensively.
The nurse transcribes an order to administer Valium 10 mg IV stat. This order is correctly interpreted by the nurse to mean it should be provided how? (Select all that apply.)
- A. As needed
- B. Immediately
- C. One time only
- D. Intravenously
Correct Answer: D
Rationale: The stat order is generally used on an emergency basis. It means that the drug is to be administered as soon as possible, but only once. IV indicates the route is intravenous. A PRN order means administer if needed. The order would specify divided doses and amount per dose if indicated.