ATI Hematologic System Related

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Which of the following anemia is associated with splenomegaly:

  • A. chronic renal failure
  • B. aplastic anemia
  • C. hereditary spherocytosis
  • D. sickle cell anaemia
Correct Answer: C

Rationale: Rationale: Hereditary spherocytosis is associated with splenomegaly due to the spleen's increased destruction of abnormal red blood cells. In this condition, red blood cells have a spherical shape, making them more prone to destruction by the spleen. Chronic renal failure (A) is not typically associated with splenomegaly. Aplastic anemia (B) is characterized by bone marrow failure and does not directly involve the spleen. Sickle cell anemia (D) leads to splenomegaly in children but not in adults due to splenic sequestration crises, making it less likely to be the correct choice.