Nokea
Which of the following bacteria is responsible for causing tuberculosis?
- A. Mycobacterium leprae
- B. Mycobacterium tuberculosis
- C. Streptococcus pneumoniae
- D. Neisseria gonorrhoeae
Correct Answer: B
Rationale: The correct answer is B: Mycobacterium tuberculosis. This bacterium is responsible for causing tuberculosis. Mycobacterium leprae (choice A) causes leprosy, not tuberculosis. Streptococcus pneumoniae (choice C) is known for causing pneumonia, not tuberculosis. Neisseria gonorrhoeae (choice D) is responsible for causing gonorrhea, not tuberculosis. Mycobacterium tuberculosis is the specific bacterium associated with tuberculosis due to its ability to infect the lungs and other organs, leading to the characteristic symptoms of the disease.
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Production of RNA from DNA is called
- A. Transposition
- B. Translation
- C. Transcription
- D. RNA splicing
Correct Answer: C
Rationale: The correct answer is C: Transcription. Transcription is the process of synthesizing RNA from a DNA template. During transcription, RNA polymerase binds to the DNA and produces a complementary RNA strand. This process is essential for gene expression.
Explanation for why other choices are incorrect:
A: Transposition involves the movement of genetic elements within a genome, not the production of RNA from DNA.
B: Translation is the process of synthesizing proteins from mRNA, not the production of RNA from DNA.
D: RNA splicing is the process of removing introns and joining exons in pre-mRNA to produce mature mRNA, not the initial production of RNA from DNA.
Typhoid fever is caused by the bacterium:
- A. Escherichia coli
- B. Salmonella enterica
- C. Shigella flexneri
- D. Staphylococcus aureus
Correct Answer: B
Rationale: The correct answer is B: Salmonella enterica. Typhoid fever is caused by the bacterium Salmonella enterica serotype Typhi. This specific strain of Salmonella is responsible for typhoid fever, a serious illness characterized by high fever, abdominal pain, and diarrhea. Escherichia coli (choice A) is not the causative agent of typhoid fever. Shigella flexneri (choice C) causes bacillary dysentery, not typhoid fever. Staphylococcus aureus (choice D) can cause food poisoning but is not associated with typhoid fever.
The major function of bacterial flagella is:
- A. Attachment to surfaces
- B. Movement of the bacterial cell
- C. Protein synthesis
- D. Nutrient absorption
Correct Answer: B
Rationale: The correct answer is B: Movement of the bacterial cell. Bacterial flagella are whip-like appendages that enable bacteria to move towards nutrients or away from harmful substances. This movement is essential for survival, dispersal, and colonization. Choice A is incorrect because attachment is primarily mediated by other structures like pili. Choice C is incorrect as protein synthesis occurs inside the cell and is not directly related to flagella. Choice D is incorrect as nutrient absorption is typically carried out through specific channels or transport systems, not by flagella.
Which of the following is a folate antagonist?
- A. Methyl Penicillin
- B. Trimethoprim
- C. Vancomycin
- D. Gentamicin
Correct Answer: B
Rationale: The correct answer is B: Trimethoprim. Trimethoprim is a folate antagonist that inhibits dihydrofolate reductase, an enzyme essential for folate metabolism in bacteria. This disrupts bacterial DNA synthesis, leading to bacteriostatic effects. Methyl Penicillin (A) is a beta-lactam antibiotic that interferes with bacterial cell wall synthesis. Vancomycin (C) inhibits cell wall synthesis by binding to D-Ala-D-Ala terminus of cell wall precursors. Gentamicin (D) inhibits bacterial protein synthesis by binding to the 30S subunit of the bacterial ribosome.
All of the following areas of the human body contain normal flora except:
- A. Peritoneum
- B. Urethra
- C. Vagina
- D. Mouth
Correct Answer: A
Rationale: The correct answer is A: Peritoneum. Normal flora refers to the microorganisms that naturally inhabit the human body without causing harm. The peritoneum is a sterile area, so it does not harbor normal flora. The urethra, vagina, and mouth all have normal flora due to their moist and warm environments, which provide an ideal habitat for microorganisms to thrive. The peritoneum, being a sterile cavity that houses organs like the stomach and intestines, does not have a natural microbial population like the other areas mentioned. Therefore, it does not contain normal flora.