Which of the following can be used with parenteral route for the treatment of diabetes mellitus
- A. Insulin preparations
- B. Sulfonilureas
- C. Biguanides
- D. Acarbose
Correct Answer: A
Rationale: Insulin is the only diabetes medication administered parenterally (e.g., subcutaneous or IV).
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Which statement is not correct regarding long acting medications:
- A. Effective for treatment of diabetes mellitus type I
- B. Effective for treatment of diabetes mellitus type II
- C. In for intravenous use
- D. Is for subcutaneous use
Correct Answer: C
Rationale: Long-acting insulins like glargine are administered subcutaneously, not intravenously, for sustained glucose control.
It is reasonable to recommend supplementation with in the treatment of hyperlipidemia.
- A. Omega-3 fatty acids
- B. Probiotics
- C. Plant sterols
- D. Calcium
Correct Answer: C
Rationale: Plant sterols reduce LDL cholesterol by inhibiting intestinal cholesterol absorption.
Rabi is being prescribed phenytoin for seizures. Monitoring includes assessing:
- A. For phenytoin hypersensitivity syndrome 3 to 8 weeks after starting treatment
- B. For pedal edema throughout therapy
- C. Heart rate at each visit and consider altering therapy if heart rate is less than 60 bpm
- D. For vision changes, such as red-green blindness, at least annually
Correct Answer: A
Rationale: Phenytoin hypersensitivity syndrome can occur 3-8 weeks post-initiation.
The nurse, assisting with Phase I drug studies, is talking with a woman who asks, Why cant I participate in this study? What would be the nurses best response?
- A. Drugs pose a greater risk to women of reproductive age.
- B. Drugs are only tested on men because they are stronger.
- C. Women are more prone to adverse effects from medications.
- D. Drugs affect women differently than they affect women.
Correct Answer: A
Rationale: Phase I drug trials usually involve healthy male volunteers because chemicals may exert an unknown and harmful effect on ova in women which could result in fetal damage when the woman becomes pregnant. Drugs are tested on both men and women, but women must be fully informed of risks and sign a consent stating they understand the potential for birth defects. Women are not more prone to adverse effects of medications. Although some drugs may affect women differently than men, this is a rationale for why drugs need to be tested on women, not an explanation of why women are not included in a Phase I study.
All the following cross placenta except
- A. Warfarin
- B. Heparin
- C. Phenindione
- D. Morphine
Correct Answer: B
Rationale: Heparin, a large molecule, does not cross the placenta; others do.
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