Which of the following causes rise in systolic as well as diastolic BP for prolonged period:
- A. Ephedrine
- B. Epinephrine
- C. Dopamine
- D. Norepinephrine
Correct Answer: D
Rationale: Norepinephrine increases both systolic and diastolic BP with prolonged effect.
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A nurse is assessing a male client who recently began taking Haloperidol. Which of the following findings is the highest priority to report to the provider?
- A. Shuffling gait
- B. Neck spasms
- C. Drowsiness
- D. Impotence
Correct Answer: B
Rationale: Neck spasms indicate dystonia, an acute extrapyramidal symptom requiring immediate attention.
Which advantage(s) does the unit dose drug distribution system include? (Select one that does not apply.)
- A. Credit is given to the patient for unused medications.
- B. The pharmacist is able to analyze prescribed medications for each client for drug interactions and contraindications.
- C. There is less waste of medications.
- D. The time spent by nursing personnel preparing these medications is increased.
Correct Answer: D
Rationale: Because the pharmacist has a profile of all medications for each patient, he or she is able to analyze prescribed medications for each patient for drug interactions and contraindications. This is an advantage of the unit dose drug distribution system. Less waste of medications is an advantage of the unit dose drug distribution system. Because each dose is individually packaged, credit can be given to the patient for unused medications. There is increased pharmacist involvement and better use of his or her extensive drug knowledge and nursing personnel time is decreased with this method.
A nurse is assessing a patient on ceftriaxone. Which allergy should be of particular concern?
- A. Sulfa
- B. Penicillin
- C. Tetracycline
- D. Macrolide
Correct Answer: B
Rationale: Ceftriaxone, a cephalosporin, has a risk of cross-reactivity with penicillin allergies due to similar beta-lactam structures.
Patient teaching related to amlodipine includes:
- A. Increase calcium intake to prevent osteoporosis from a calcium blockade.
- B. Do not crush the tablet; it must be given in liquid form if the patient has trouble swallowing it.
- C. Avoid grapefruit juice as it affects the metabolism of this drug.
- D. Rise slowly from a supine position to reduce orthostatic hypotension.
Correct Answer: C
Rationale: Grapefruit juice inhibits CYP3A4, increasing amlodipine levels.
A 7-year-old male fell off a wood pile while playing. He has been admitted to the ICU with multiple broken bones and internal bleeding. What should the nurse know about drug therapy in this type of patient?
- A. Adverse effects may be decreased
- B. Therapeutic effects may be increased
- C. Pharmacodynamics may be altered
- D. Pharmacokinetics remain the same
Correct Answer: C
Rationale: Trauma alters pharmacodynamics (drug effects) due to physiological stress and injury responses.