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Which of the following clinical features is most characteristic of acute respiratory distress syndrome (ARDS)?
- A. Hypoxemia refractory to supplemental oxygen
- B. Severe cough with purulent sputum production
- C. Chest pain exacerbated by deep breathing
- D. Productive cough with hemoptysis
Correct Answer: A
Rationale: Acute respiratory distress syndrome (ARDS) is a serious and life-threatening condition characterized by rapid onset of respiratory failure, severe hypoxemia (low oxygen levels in the blood), and non-cardiogenic pulmonary edema. The hallmark of ARDS is severe hypoxemia that is difficult to correct even with high levels of supplemental oxygen. Patients with ARDS often require mechanical ventilation to maintain adequate oxygen levels. Severe cough with purulent sputum production, chest pain exacerbated by deep breathing, and productive cough with hemoptysis are not typical features of ARDS.
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Which of the following mechanisms is responsible for the phenomenon of immunological memory, wherein the immune system mounts a faster and more robust response upon re-exposure to a previously encountered pathogen?
- A. Clonal expansion of memory B cells
- B. Differentiation of na(cid:239)ve T cells into effector T cells
- C. Production of antibodies by plasma cells
- D. Activation of the complement system
Correct Answer: A
Rationale: Immunological memory is primarily maintained by the clonal expansion of memory B cells. Memory B cells are a type of long-lived immune cell that originates from previously activated B cells during an immune response to a pathogen. When the immune system encounters the same pathogen again, memory B cells can quickly recognize and respond to it by undergoing rapid clonal expansion and differentiation into plasma cells that produce specific antibodies. This quick and robust response leads to the more efficient elimination of the pathogen during secondary exposure, resulting in the faster and stronger immune response characteristic of immunological memory.
A patient presents with recurrent episodes of sudden, severe vertigo lasting hours, accompanied by nausea, vomiting, and nystagmus. Vestibular function tests demonstrate unilateral weakness. Which of the following conditions is most likely responsible for this presentation?
- A. Vestibular neuritis
- B. Benign paroxysmal positional vertigo (BPPV)
- C. Ménière's disease
- D. Acoustic neuroma Ophthalmology
Correct Answer: A
Rationale: The patient's presentation of recurrent episodes of sudden, severe vertigo lasting hours with nausea, vomiting, and nystagmus, along with unilateral weakness on vestibular function tests, is most consistent with vestibular neuritis. Vestibular neuritis is characterized by inflammation of the vestibular nerve leading to sudden onset vertigo that can last for hours to days. It is often associated with nausea, vomiting, and nystagmus. Unilateral weakness on vestibular function tests indicates dysfunction of one vestibular system. Differential diagnosis for this type of presentation includes other conditions such as Meniere's disease, BPPV, and acoustic neuroma. However, the combination of symptoms and unilateral vestibular weakness makes vestibular neuritis the most likely diagnosis in this case.
Which is the MOST important risk factor to osteoporosis
- A. Menopause
- B. With history of previous fracture
- C. Being male
- D. Short in height
Correct Answer: A
Rationale: Menopause is the most important risk factor for osteoporosis because it leads to a decrease in estrogen levels, which plays a crucial role in maintaining bone density. After menopause, women are at a higher risk of developing osteoporosis due to loss of estrogen's protective effects on bone mass. Other risk factors like history of previous fracture, being male, and short stature can also contribute to osteoporosis, but menopause has the strongest association with the development of the condition. It is essential for postmenopausal women to be aware of this risk factor and take preventive measures such as regular exercise, adequate calcium and vitamin D intake, and appropriate medical evaluation and treatment as needed.
Choose an indicator that models personal and professional behavior and values.
- A. Utilizes communication and social media responsibly
- B. Attends conferences
- C. Enrolls in school
- D. Joins civic organization
Correct Answer: A
Rationale: Utilizing communication and social media responsibly is an indicator that models personal and professional behavior and values. Responsible use of communication and social media demonstrates a commitment to maintaining a positive online presence, interacting respectfully with others, and upholding professional standards in digital communication. This behavior reflects integrity, accountability, and respect for oneself and others, which are essential qualities in both personal and professional settings. Additionally, demonstrating responsible behavior in the digital sphere can help build trust, enhance reputation, and foster valuable relationships with colleagues, clients, and the community.
Which of the following is caused by the markedly distended uterus and intermittent uterine contractions within 2 to 3 days after birth?
- A. Retained placenta
- B. Uterine atony
- C. Afterpains
- D. Boggy uterus
Correct Answer: B
Rationale: Uterine atony is caused by the markedly distended uterus and intermittent uterine contractions within 2 to 3 days after birth. It is characterized by the inability of the uterus to contract after delivery, leading to excessive bleeding postpartum. This condition is a significant risk factor for postpartum hemorrhage. Treatment may involve massage of the uterus, administration of uterotonics, and in severe cases, surgical interventions such as a hysterectomy. Retained placenta refers to incomplete expulsion of the placenta after delivery. Afterpains are the discomfort felt by some women as their uterus contracts and returns to its normal size after childbirth. A boggy uterus is another term for a uterus that feels soft, lax, or lack firm tone, which can be a sign of uterine atony.