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Which of the following conditions is characterized by inflammation of the prostate gland, typically presenting with dysuria, urinary frequency, urgency, and perineal or pelvic pain?
- A. Prostate cancer
- B. Benign prostatic hyperplasia (BPH)
- C. Prostatitis
- D. Urethritis
Correct Answer: C
Rationale: Prostatitis is characterized by inflammation of the prostate gland, leading to symptoms such as dysuria (painful urination), urinary frequency, urinary urgency, and perineal or pelvic pain. Prostate cancer, on the other hand, is characterized by the presence of malignant cells in the prostate gland and may not present with these typical symptoms. Benign prostatic hyperplasia (BPH) is a non-cancerous enlargement of the prostate gland that can cause urinary symptoms but is not typically associated with inflammation. Urethritis refers to inflammation of the urethra, which is a different condition and may present with symptoms such as painful urination and discharge from the urethra.
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A patient presents with fever, malaise, and a skin lesion resembling a "bull's eye" rash at the site of a tick bite. Which of the following is the most likely causative agent?
- A. Plasmodium falciparum
- B. Trypanosoma cruzi
- C. Borrelia burgdorferi
- D. Leishmania donovani
Correct Answer: C
Rationale: The most likely causative agent in this scenario is Borrelia burgdorferi, which is the bacterium responsible for causing Lyme disease. The classic presentation of Lyme disease includes fever, malaise, and a skin lesion resembling a "bull's eye" rash, known as erythema migrans. This rash typically appears at the site of a tick bite. If left untreated, Lyme disease can progress to involve multiple organ systems and lead to more severe complications. Plasmodium falciparum is the causative agent of malaria, which typically presents with symptoms such as fever, chills, and fatigue, but it does not cause a "bull's eye" rash. Trypanosoma cruzi is the parasite responsible for Chagas disease, which presents with symptoms such as fever, swelling at the site of entry (typically the bite wound), and enlarged lymph nodes, but it does not
A patient presents with recurrent episodes of epistaxis, gum bleeding, and easy bruising. Laboratory tests reveal prolonged bleeding time, normal platelet count, and normal PT and aPTT. Which of the following conditions is most likely to cause these findings?
- A. Von Willebrand disease
- B. Glanzmann thrombasthenia
- C. Hemophilia A
- D. Bernard-Soulier syndrome
Correct Answer: A
Rationale: The clinical presentation of recurrent episodes of epistaxis, gum bleeding, and easy bruising, along with laboratory findings of prolonged bleeding time, normal platelet count, and normal coagulation studies (PT and aPTT) are highly suggestive of Von Willebrand disease. Von Willebrand disease is the most common inherited bleeding disorder and is characterized by a deficiency or dysfunction of von Willebrand factor (vWF), which plays a key role in platelet adhesion and aggregation. The prolonged bleeding time is due to impaired platelet adhesion to the damaged vessel wall in the absence of functional vWF. Normal platelet count and normal PT/aPTT help differentiate Von Willebrand disease from other bleeding disorders such as hemophilia and platelet function disorders like Glanzmann thrombasthenia and Bernard-Soulier syndrome.
Which of the following dental conditions is characterized by the abnormal wearing away of tooth structure due to factors such as bruxism or acidic erosion?
- A. Dental caries
- B. Attrition
- C. Abrasion
- D. Erosion
Correct Answer: B
Rationale: Attrition is the dental condition characterized by the abnormal wearing away of tooth structure due to factors such as bruxism (grinding or clenching of teeth) or acidic erosion. Bruxism can cause tooth-to-tooth contact that leads to the wearing down of the tooth enamel and eventually can affect deeper layers of the tooth. Acidic erosion, on the other hand, is caused by the direct contact of teeth with acidic substances, which can lead to the gradual loss of tooth structure over time. Dental caries refers to tooth decay caused by bacteria, abrasion involves wearing away of tooth structure due to external factors like improper brushing habits, and erosion specifically relates to the loss of tooth structure caused by acidic substances.
A patient presents with chest pain that occurs at rest and is relieved by nitroglycerin. An electrocardiogram (ECG) may show transient ST-segment elevation. Which cardiovascular disorder is most likely responsible for these symptoms?
- A. Stable angina
- B. Unstable angina
- C. Acute myocardial infarction
- D. Prinzmetal's angina
Correct Answer: D
Rationale: Prinzmetal's angina, also known as variant angina, is characterized by episodes of chest pain that occur at rest and are relieved by nitroglycerin. Patients with Prinzmetal's angina may also have transient ST-segment elevation on an electrocardiogram (ECG) during episodes of chest pain. This is due to coronary artery vasospasm, which causes temporary obstruction of blood flow to the heart muscle. Stable angina typically presents with chest pain on exertion that resolves with rest, while unstable angina and acute myocardial infarction present with chest pain that is not relieved with nitroglycerin and are associated with more severe coronary artery disease.
Which endocrine disorder is most likely responsible for these symptoms?
- A. Hashimoto's thyroiditis
- B. Graves' disease
- C. Diabetes mellitus
- D. Thyroid nodules
Correct Answer: B
Rationale: The symptoms described—tachycardia, weight loss, and tremors—are consistent with hyperthyroidism. Graves' disease is the most common cause of hyperthyroidism and is an autoimmune disorder in which the thyroid gland is overactive. This condition can lead to an increased production of thyroid hormones, resulting in symptoms such as rapid heartbeat (tachycardia), unintended weight loss, and tremors. In contrast, Hashimoto's thyroiditis is an autoimmune disorder that causes hypothyroidism, leading to symptoms like fatigue, weight gain, and cold intolerance. Diabetes mellitus is a metabolic disorder characterized by high blood sugar levels, which typically presents with symptoms such as increased thirst, frequent urination, and fatigue. Thyroid nodules are growths within the thyroid gland that can sometimes be associated with overactive (hyperthyroidism) or underactive (hypothyroidism) thyroid function, but they do not