Which of the following diagnostic studies would NOT indicate a problem related to a reductase inhibitor?
- A. Elevated serum transaminase
- B. Increased serum creatinine
- C. Elevated creatinine kinase
- D. Increased white blood cell counts
Correct Answer: D
Rationale: WBC elevation is unrelated to reductase inhibitors; others indicate liver, kidney, or muscle issues.
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Hepatitis B immune globulin is administered to provide passive immunity to:
- A. Infants born to HBsAg-positive mothers
- B. Household contacts of hepatitis-B virus infected people
- C. Persons exposed to blood containing hepatitis B virus
- D. All of the above
Correct Answer: D
Rationale: Hepatitis B immune globulin provides passive immunity in all listed exposure scenarios .
A nurse is caring for a client who has a new prescription for Niacin to reduce cholesterol. The nurse should monitor for which of the following findings as an adverse effect of Niacin?(Select one that does not apply.)
- A. Jaundice
- B. Hyperglycemia
- C. Hearing loss
- D. Flushing of the skin
Correct Answer: C
Rationale: Niacin causes hyperglycemia , flushing , and jaundice from liver effects.
Phenylephrine is useful for all of the following except
- A. Anaphylactic shock
- B. Mydriasis
- C. Nasal decongestant
- D. Artial tachycardia
Correct Answer: A
Rationale: Phenylephrine (alpha-agonist) is not used in anaphylactic shock (epinephrine is preferred).
The client with squamous cell carcinoma of the larynx is receiving bleomycin intravenously. The nurse caring for the client anticipates that which diagnostic study will be prescribed?
- A. Echocardiography
- B. Electrocardiography
- C. Cervical radiography
- D. Pulmonary function studies
Correct Answer: D
Rationale: Bleomycin is an antineoplastic medication (Chemotherapeutic Agents) that can cause interstitial pneumonitis, which can progress to pulmonary fibrosis. Pulmonary function studies along with hematological, hepatic, and renal function tests need to be monitored. The nurse needs to monitor lung sounds for dyspnea and crackles, which indicate pulmonary toxicity. The medication needs to be discontinued immediately if pulmonary toxicity occurs. Options 1, 2, and 3 are unrelated to the specific use of this medication.
A nurse is working as a member of a research team involved in exploring the unique response to drugs each individual displays based on genetic make-up. What is this area of study is called?
- A. Pharmacotherapeutics
- B. Pharmacodynamics
- C. Pharmacoeconomics
- D. Pharmacogenomics
Correct Answer: D
Rationale: Pharmacogenomics is the area of study that includes mapping of the human genome. In the future, medical care and drug regimens may be personally designed based on a patient's unique genetic make-up. Pharmacotherapeutics is the branch of pharmacology that deals with the uses of drugs to treat, prevent, and diagnose disease. Pharmacodynamics involves how a drug affects the body. Pharmacoeconomics includes the costs involved in drug therapy.
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