BZDs may be used in following situations EXCEPT:
- A. Anaesthesia
- B. Anxiety
- C. Floppy infant syndrome
- D. Epilepsy
Correct Answer: C
Rationale: Benzodiazepines (BZDs) are used in anesthesia, anxiety, and epilepsy, but floppy infant syndrome is a side effect of maternal BZD use, not a condition treated with them.
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Why is diclofenac combined with misoprostol?
- A. They are synergistic
- B. They are additive
- C. To reduce hepatic side effects
- D. To prevent diclofenac-related gastric ulcers
Correct Answer: D
Rationale: Misoprostol protects against diclofenac-induced gastric ulcers.
Where would the procedures and treatments directed by the health care provider be found?
- A. Summary sheet
- B. Physician's order form
- C. Physician's progress notes
- D. History and physical examination form
Correct Answer: B
Rationale: The physician's order form contains all procedures and treatments ordered by the health care provider. A summary sheet provides a brief overview of the hospital course at discharge. Physician's progress notes provide regular observations on the patient's course of treatment and response. A history and physical examination form provides information about baseline information from the patient.
Hepatitis B immune globulin is administered to provide passive immunity to:
- A. Infants born to HBsAg-positive mothers
- B. Household contacts of hepatitis-B virus infected people
- C. Persons exposed to blood containing hepatitis B virus
- D. All of the above
Correct Answer: D
Rationale: Hepatitis B immune globulin provides passive immunity in all listed exposure scenarios .
All the following cross placenta except
- A. Warfarin
- B. Heparin
- C. Phenindione
- D. Morphine
Correct Answer: B
Rationale: Heparin, a large molecule, does not cross the placenta; others do.
A 66-year-old man is admitted to the hospital with confusion, nausea, and blurred vision. He is currently on digoxin for the treatment of heart failure. On physical exam, his heart rate is 120 bpm. Further evaluation reveals a digoxin level of 5.3 ng/mL (normal range: 0.5-2 ng/mL). The doctor believes his symptoms are due to digoxin toxicity. Which parameter is used to indicate the ability of digoxin to produce the desired effect relative to a toxic effect?
- A. Bioavailability
- B. Efficacy
- C. Intrinsic activity
- D. Therapeutic index
Correct Answer: D
Rationale: Therapeutic index (TI) measures the relative safety of a drug by comparing the dose required for a therapeutic effect to the dose that produces toxicity. In this case, digoxin toxicity is indicated by the elevated level, and TI is the relevant parameter.