Nokea
Which of the following does albumin have the strongest affinity for?
- A. Anionic drugs
- B. Hydrophilic drugs
- C. Hydrophobic drugs
- D. A and C
Correct Answer: C
Rationale: Albumin has the strongest affinity for hydrophobic drugs , which bind to its hydrophobic pockets, unlike hydrophilic drugs; anionic drugs may bind but less preferentially.
You may also like to solve these questions
Which phenothiazine has the least extra pyramidal effect
- A. Thioridazine
- B. Chlorpromazine
- C. Triflupromazine
- D. Fluphenazine
Correct Answer: A
Rationale: Thioridazine has fewer extrapyramidal effects.
A pharmaceutical lab states that a drug causes negative side effects in 3 of every 100 patients. To confirm this affirmation, another laboratory chooses 5 people at random who have consumed the drug. What is the probability that at least two experience side effects?
- A. 0.8687
- B. 0.1313
- C. 0.00847
- D. 0.0003
Correct Answer: C
Rationale: The probability of at least two experiencing side effects is P(X≥2) = 1 - [P(X=0) + P(X=1)]. Using binomial calculations: P(X=0) = 0.8687, P(X=1) = (5 choose 1) * 0.03 * 0.97^4 = 0.1342, so P(X≥2) = 1 - (0.8687 + 0.1342) = 0.00847, matching the document.
A nurse has received an order to administer two drugs at the same time of the day. The nurse should first:
- A. Wash her hands before handling the medications
- B. Consult a drug guide for compatibility
- C. Question the patient concerning drug allergies
- D. Identify the patient by checking the armband and asking the patient to state his or her name
Correct Answer: B
Rationale: Consulting a drug guide for compatibility is critical to avoid adverse interactions when administering two drugs simultaneously. Hand washing, allergy checks, and patient identification are also essential but follow ensuring drug compatibility to prevent harm.
A nurse in a clinic is caring for a group of clients. The nurse should contact the provider about a potential contraindication to a medication for which of the following clients?
- A. A client at 8 weeks of gestation who asks for an influenza immunization
- B. A client who takes Prednisolone and has a no fungal infection
- C. A client who has chronic liver disease and is taking hydrocortone
- D. A client who has Peptic Ulcer Disease, takes Sucralfate, and tells the nurse she has started taking OTC Aluminum Hydroxide
Correct Answer: C
Rationale: Prednisolone worsens fungal infections, hydrocortisone is risky in liver disease, and warfarin with pregnancy increases bleeding risk.
Scopolamine can be used to prevent the nausea and vomiting associated with motion sickness. The patient is taught to:
- A. Apply the transdermal disk at least 4 hours before the antiemetic effect is desired.
- B. Swallow the tablet 1 hour before traveling where motion sickness is possible.
- C. Place the tablet under the tongue and allow it to dissolve.
- D. Change the transdermal disk daily for maximal effect.
Correct Answer: A
Rationale: Scopolamine patches require 4 hours for onset, making preemptive application key.