Nokea
Which of the following drugs do not cross the placenta
- A. Dilantin
- B. Diazepam
- C. Acinocoumarin
- D. Heparin
Correct Answer: D
Rationale: Heparin does not cross the placenta due to its large size.
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Slow channel syndrome is due to
- A. Accumulation of Na+ ions in channels
- B. Accumulation of K+ ions in channels
- C. Accumulation of Mg++ ions in channels
- D. Accumulation of Ca++ ions in channels
Correct Answer: D
Rationale: Slow channel syndrome relates to calcium channel dysfunction.
A nurse is teaching a client who has a new prescription for Verapamil to control Hypertension. Which of the following instructions should the nurse include?
- A. Increase the amount of dietary fiber in the diet.
- B. Drink grapefruit juice daily to increase vitamin C intake.
- C. Decrease the amount of calcium in the diet.
- D. Withhold food for 1 hr after the medication is taken
Correct Answer: A
Rationale: Fiber prevents constipation, a common side effect of verapamil; grapefruit juice interacts adversely.
Angina is caused by:
- A. Blocking beta1 receptors with a constant binding of noradrenaline
- B. Activating beta2 receptors
- C. Beta1 receptors are not active anymore
- D. Extreme binding of noradrenaline due to up regulation
Correct Answer: D
Rationale: Angina results from myocardial ischemia, often due to excessive demand or reduced supply, which can be exacerbated by upregulated noradrenaline binding increasing heart workload.
Which of the following produced by the pancreatic alfa cells:
- A. Insulin
- B. Glucagon
- C. C-peptide
- D. Somatostatin
Correct Answer: B
Rationale: Glucagon is produced by pancreatic alpha cells to raise blood glucose.
AH are prodrugs except
- A. Enalapril
- B. Paracetamol
- C. Sulphamethoxazole
- D. Trimethoprim
Correct Answer: D
Rationale: Enalapril is a prodrug; paracetamol, sulphamethoxazole, and trimethoprim are active drugs.