Nokea
Which of the following drugs is associated with extreme photosensitivity as a reaction?
- A. Digitalis
- B. Niacin
- C. Tetracycline
- D. Fluoroquinolones
Correct Answer: C
Rationale: The correct answer is C: Tetracycline. Tetracycline is associated with extreme photosensitivity due to its mechanism of action causing phototoxic reactions when exposed to sunlight. Digitalis (A) is a cardiac medication, niacin (B) is a B vitamin, and fluoroquinolones (D) are antibiotics, none of which are known to cause extreme photosensitivity reactions.
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Which of the following conditions is not treated with epinephrine?
- A. Renal disease
- B. Asthma
- C. Hypotension
- D. Glaucoma
Correct Answer: A
Rationale: The correct answer is A: Renal disease. Epinephrine is not used to treat renal disease because it can potentially worsen kidney function. Epinephrine is used in asthma to dilate the airways, in hypotension to increase blood pressure, and in glaucoma to reduce intraocular pressure. Treating renal disease with epinephrine can lead to further complications due to its effect on blood flow and kidney function. Therefore, renal disease is not treated with epinephrine to avoid exacerbating kidney issues.
Which of the following drugs is associated with the reaction of tendon dysfunction?
- A. Digitalis
- B. Niacin
- C. Tetracycline
- D. Fluoroquinolones
Correct Answer: D
Rationale: The correct answer is D: Fluoroquinolones. Fluoroquinolones are known to be associated with tendon dysfunction due to their potential to cause tendinitis and tendon rupture. This adverse effect is thought to be related to the drug's ability to disrupt collagen synthesis and structure in tendons. Digitalis (A) is used to treat heart conditions, niacin (B) for cholesterol, and tetracycline (C) for bacterial infections, none of which are linked to tendon dysfunction.
Which of the following is considered a class IA Sodium Channel blocker?
- A. Mexiletine
- B. Amiodarone
- C. Quinidine
- D. Procainamide
Correct Answer: D
Rationale: The correct answer is D: Procainamide. Procainamide is a class IA antiarrhythmic drug that blocks sodium channels, prolonging the action potential duration. This helps to stabilize the heart's rhythm. Mexiletine (A) is a class IB antiarrhythmic drug that blocks sodium channels with fast recovery kinetics. Amiodarone (B) is a class III antiarrhythmic drug that prolongs repolarization by blocking potassium channels. Quinidine (C) is a class IA antiarrhythmic drug that also blocks sodium channels, but it is not a class IB sodium channel blocker like Procainamide.
Which of the following conditions are not treated with opioid analgesics like dextromethorphan and methadone?
- A. Pulmonary Edema
- B. Cough suppression
- C. Sedation
- D. Pain
Correct Answer: C
Rationale: The correct answer is C: Sedation. Opioid analgesics like dextromethorphan and methadone are primarily used for pain management, not sedation. They work by binding to opioid receptors in the brain to reduce pain perception. Pulmonary edema can be managed with diuretics, cough suppression with antitussives, and sedation with sedatives/hypnotics. Therefore, sedation is not a condition typically treated with opioid analgesics.
Which of the following conditions are not treated with Barbiturates?
- A. Seizures
- B. Hypotension
- C. Insomnia
- D. Anxiety
Correct Answer: B
Rationale: Barbiturates are central nervous system depressants used to treat seizures, insomnia, and anxiety. However, they can worsen hypotension as they can cause vasodilation and decrease blood pressure. Choice B is correct because using barbiturates in hypotensive patients can lead to further lowering of blood pressure, potentially causing harm. Choices A, C, and D are incorrect as barbiturates are commonly used to treat seizures, insomnia, and anxiety, respectively, due to their sedative and anticonvulsant properties.