Nokea
Which of the following drugs is used for the management of atropine intoxication?
- A. Physostigmine
- B. Neostigmine
- C. Endrophonium
- D. Donepezil
Correct Answer: A
Rationale: Physostigmine, a cholinesterase inhibitor, crosses the BBB to reverse atropine's central effects.
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A nurse is caring for a client who received IV Verapamil to treat supraventricular tachycardia (SVT). The client's pulse rate is now 98/min and his blood pressure is 74/44 mg hg. The nurse should anticipate a prescription for which of the following IV medications?
- A. Calcium gluconate
- B. Sodium bicarbonate
- C. Potassium chloride
- D. Magnesium sulfate
Correct Answer: A
Rationale: Calcium gluconate reverses verapamil-induced hypotension by counteracting calcium channel blockade.
A pharmaceutical lab states that a drug causes negative side effects in 3 of every 100 patients. To confirm this affirmation, another laboratory chooses 5 people at random who have consumed the drug. What is the average number of patients that the laboratory should expect to experience side effects if they choose 100 patients at random?
- A. 1
- B. 2
- C. 3
- D. 4
Correct Answer: C
Rationale: The expected value (mean) of a binomial distribution is n * p. Here, n=100 and p=0.03, so U = 100 * 0.03 = 3, as calculated in the document.
When taken with aminoglycosides, platinum chemotherapy or cyclosporin increase the risk of
- A. Kidney damage
- B. Ototoxicity
Correct Answer: A
Rationale: Platinum chemotherapy (e.g., cisplatin) and cyclosporin both potentiate aminoglycoside nephrotoxicity, increasing kidney damage risk.
The combination of propranolol & nifedipine in essential hypertension is used because
- A. CNS effects of propanolol are prevented
- B. Pedal edema of nifedipine is prevented
- C. Alteration of serum lipids by propranolol is prevented
- D. Reflex sympathetic activity of nifedipine is prevented
Correct Answer: D
Rationale: Propranolol (beta-blocker) counters nifedipine's (calcium channel blocker) reflex tachycardia.
Which of the following has a strong anti-inflammatory effect:
- A. Prednisolone
- B. Triamcinolone
- C. Dexamethasone
- D. Prednisone
Correct Answer: C
Rationale: Dexamethasone has a strong anti-inflammatory effect due to its high glucocorticoid potency.