Nokea
Which of the following elements is required for the synthesis of thyroid hormone?
- A. copper
- B. iodine
- C. sulfur
- D. zinc
Correct Answer: B
Rationale: The correct answer is B: iodine. Iodine is an essential element required for the synthesis of thyroid hormone. Thyroid hormones such as thyroxine (T4) and triiodothyronine (T3) contain iodine atoms. Without sufficient iodine, the thyroid gland cannot produce these hormones, leading to thyroid disorders like hypothyroidism or goiter. Copper (A), sulfur (C), and zinc (D) are not directly involved in the synthesis of thyroid hormone. Copper is important for enzyme function, sulfur is present in amino acids, and zinc is involved in various cellular processes but not specifically in thyroid hormone synthesis.
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Which of the following drugs has muscarinic and nicotinic actions and is resistant to hydrolysis by both true and pseudo cholinesterase:
- A. Acetylcholine
- B. Carbachol
- C. Bethanechol
- D. Succinylcholine
Correct Answer: B
Rationale: Step-by-step rationale for why B (Carbachol) is the correct answer:
1. Carbachol is a cholinergic drug that acts on both muscarinic and nicotinic receptors.
2. It is resistant to hydrolysis by both true and pseudo cholinesterase enzymes.
3. Acetylcholine (A) is rapidly hydrolyzed by both cholinesterases.
4. Bethanechol (C) is a muscarinic agonist but not a nicotinic agonist.
5. Succinylcholine (D) is a depolarizing neuromuscular blocking agent, not a cholinergic agonist.
Summary:
Carbachol is the only drug among the choices that has both muscarinic and nicotinic actions and is resistant to hydrolysis by cholinesterases. Acetylcholine is rapidly hydrolyzed, Bethanechol does not have nicotinic actions, and Succinyl
Which of the following is descriptive of prolactin?
- A. Secreted by the posterior pituitary gland.
- B. Also called lactogenic hormone.
- C. Causes the milk let-down reflex.
- D. Stimulates the neurohypophysis to synthesize oxytocin.
Correct Answer: B
Rationale: Step-by-step rationale:
1. Prolactin is also called lactogenic hormone, as it promotes milk production in the mammary glands.
2. Secreted by the anterior pituitary gland, not the posterior pituitary gland.
3. Milk let-down reflex is primarily controlled by oxytocin, not prolactin.
4. Prolactin does not stimulate the neurohypophysis (posterior pituitary) to synthesize oxytocin.
Summary:
Choice B is correct because it accurately describes the function of prolactin in promoting lactation. Choices A, C, and D are incorrect due to inaccuracies in the functions and secretion of prolactin.
Name the structure that prevents food from entering the lungs?
- A. Pyloric sphincter
- B. Trachea
- C. Pharynx
- D. Epiglottis
Correct Answer: D
Rationale: The correct answer is D: Epiglottis. The epiglottis is a flap of tissue that covers the trachea during swallowing, preventing food from entering the lungs. When food is swallowed, the epiglottis closes off the trachea to ensure that the food goes down the esophagus into the stomach.
Incorrect choices:
A: The pyloric sphincter is a valve located between the stomach and the small intestine, regulating the flow of partially digested food.
B: The trachea is the windpipe that connects the larynx to the bronchi, allowing air to pass into the lungs.
C: The pharynx is the throat area where the pathways for both food and air cross, but it is the epiglottis that specifically prevents food from entering the lungs.
Enlargement of the thyroid gland:
- A. is called a goiter.
- B. causes Addisonian crisis.
- C. makes a person appear cushingoid.
- D. causes hypocalcemic tetany.
Correct Answer: A
Rationale: Step-by-step rationale for why choice A is correct:
1. Enlargement of the thyroid gland is known as a goiter.
2. A goiter can result from various conditions like iodine deficiency or thyroid disorders.
3. It is a common sign of thyroid dysfunction.
4. Goiter may or may not cause symptoms depending on the underlying cause.
5. Therefore, choice A is the correct answer.
Summary:
- Choice B (Addisonian crisis) is incorrect as it is associated with adrenal insufficiency, not thyroid enlargement.
- Choice C (cushingoid appearance) is incorrect as it is related to excess cortisol production, not thyroid enlargement.
- Choice D (hypocalcemic tetany) is incorrect as it is due to low calcium levels, not thyroid enlargement.
Complete the following sentence: Calcium homeostasis is controlled by…
- A. Insulin
- B. Erythropoietin
- C. Aldosterone
- D. Parathyroid hormone
Correct Answer: D
Rationale: The correct answer is D: Parathyroid hormone. Parathyroid hormone plays a crucial role in regulating calcium homeostasis by increasing calcium levels in the blood through various mechanisms. It promotes calcium release from bones, enhances calcium absorption in the intestines, and reduces calcium excretion from the kidneys. Insulin (Choice A) primarily regulates blood sugar levels, not calcium. Erythropoietin (Choice B) stimulates red blood cell production and does not directly affect calcium homeostasis. Aldosterone (Choice C) regulates sodium and potassium balance but not calcium levels. Thus, Parathyroid hormone is the correct choice for controlling calcium homeostasis.